July 2018
Volume 59, Issue 9
Open Access
ARVO Annual Meeting Abstract  |   July 2018
Efficacy of Micropulse Laser in Treatment of Idiopathic Polypoidal Choroidal Vasculopathy (IPCV) Unresponsive to Aflibercept Injections
Author Affiliations & Notes
  • Ahmed ALNAHRAWY
    Western Eye Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom
    Suez Canal University, Faculty of Medicine, Ismailia, Egypt
  • Abike Goodluck
    Western Eye Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom
  • Saad Younis
    Western Eye Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom
  • Footnotes
    Commercial Relationships   Ahmed ALNAHRAWY, None; Abike Goodluck, None; Saad Younis, None
  • Footnotes
    Support  none
Investigative Ophthalmology & Visual Science July 2018, Vol.59, 75. doi:
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      Ahmed ALNAHRAWY, Abike Goodluck, Saad Younis; Efficacy of Micropulse Laser in Treatment of Idiopathic Polypoidal Choroidal Vasculopathy (IPCV) Unresponsive to Aflibercept Injections . Invest. Ophthalmol. Vis. Sci. 2018;59(9):75.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : Establish efficacy of Micropulse laser (MPL) for IPCV Aflibercept resistant cases
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Methods : Six Eyes of six patients were diagnosed with IPCV based on Indocyanine Green Angiography were treated monthly with Aflibercept injections and were unresponsive. Unresponsive cases were defined as those with no change in VA or PED reduction in height after 3 monthly Aflibercept injections. Micropulse laser was focally applied for areas of PED or obvious leaking spot, parameters were customised according to individual variability. Eyes were examined at weeks 4, 8 and 12 after laser with concomitant Aflibercept injections
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Results : Five eyes showed positive changes after MPL, while one eye had no difference. There is a trend in the response, at week4 the PED is more in size, with increase in height as measured in microns on OCT, while it would reduce up to week 12 of our observation, difference is statistically significant when compared to aflibercept only eyes. Changes in visual acuity was not of any statisitical significance
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Conclusions : Micropulse laser treatments can be a safe augmentation with aflibercept injections to maximise response to treatment in cases of unresponsive IPCV. Further studies to be performed for generalizability.
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This is an abstract that was submitted for the 2018 ARVO Annual Meeting, held in Honolulu, Hawaii, April 29 - May 3, 2018.

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