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Hongyan Zhang, Mozhu Li, Xudong Song, Hongxin Song; Comparison of Corneal Endothelial Cell Changes after Phacoemulsification using Different Viscosurgical Devices. Invest. Ophthalmol. Vis. Sci. 2018;59(9):445.
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© ARVO (1962-2015); The Authors (2016-present)
To compare the performance of two different ophthalmic viscosurgical devices: Duovisc (OVD1, Alcon Laboratories, Inc) and viscoelastic solution (OVD2, Singclean Medical, Inc) in phacoemulsification and intraocular lens implantation surgery.
158 eyes from 100 patients with cataract had phacoemulsification and intraocular lens implantation were included in this study. Patients were randomly assigned to receive OVD1 (73 eyes) and OVD2 (85 eyes) during the surgery and all surgeries were done by the same surgeon. Preoperative and postoperative examinations over 1 month including corneal endothelial cell density (CECD), central corneal thickness (CCT) and cell panchymetry were measured. Independent t test was used to compare the percent changes of endothelial cell density and central corneal thickness.
One month postoperatively, corneal endothelial cell loss is statistically lower in OVD1 group than OVD2 group (-6.83% vs -13.34%, p=0.008). CCT change is lower in OVD1 group than OVD2 group (0.017% vs 1.63%, p=0.009). Subjectively, the OVD 2 was easier to use, whereas the OVD1 has better performance for protecting corneal endothelial cells.
OVD1 has better cohesive and dispersive properties and has better performance to protect corneal endothelial cells during cataract surgery compared to OVD2.
This is an abstract that was submitted for the 2018 ARVO Annual Meeting, held in Honolulu, Hawaii, April 29 - May 3, 2018.
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