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YU MIZUNO, Yoshiaki Kiuchi; Effects of trabeculectomy on optical characteristics. Invest. Ophthalmol. Vis. Sci. 2018;59(9):451.
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© ARVO (1962-2015); The Authors (2016-present)
Trabeculectomy is an effective surgery for lowering intraocular pressure to slow the progression of visual field loss in glaucoma patients; however, patients sometimes complain of changes in vision postoperatively. Recently, advances in ocular aberrometry have revealed that ocular surgeries increase ocular and corneal higher-order aberrations. The purpose of this retrospective nonrandomized study is to examine the effects of trabeculectomy on corneal higher-order wavefront aberration and anterior segment optical coherence tomography images.
Sixty-three eyes from 50 patients after trabeculectomy with a limbal-based conjunctival flap and 23 eyes from 16 normal patients were included. Corneal higher-order aberration for a 4-mm pupil diameter and corneal astigmatism were measured using TOPCON KR-1W wavefront analyzer. Keratometric, posterior, and real astigmatism were measured using TOMEY CASIA 2. Student-t test and Wilcoxon rank sum test were used for statistical analyses.
Corneal higher-order aberration was statistically significantly higher in the trabeculectomy group than in the normal group (0.35 ± 0.04 μm and 0.17 ± 0.08 μm, respectively; P < 0.001). Corneal astigmatism was also increased in the trabeculectomy group than in the normal group (−2.17 ± 0.28 μm and −1.28 ± 0.45 μm, respectively; P = 0.049). Keratometric and posterior astigmatism were higher in the trabeculectomy group (43.91 ± 0.20 D and −6.18 ± 0.03 D) than in the normal group (43.06 ± 0.35 D and −6.04 ± 0.04 D, respectively; P = 0.038 and P = 0.005). Real astigmatism was not different between the two groups (42.88 ± 0.20 D and 42.06 ± 0.36 D, respectively; P = 0.050).
Trabeculectomy with a limbal-based conjunctival flap increases not only corneal astigmatism but also higher-order aberrations.
This is an abstract that was submitted for the 2018 ARVO Annual Meeting, held in Honolulu, Hawaii, April 29 - May 3, 2018.
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