July 2018
Volume 59, Issue 9
Open Access
ARVO Annual Meeting Abstract  |   July 2018
Functional properties of human retina measured with Adaptive Optics
Author Affiliations & Notes
  • Austin Roorda
    School of Optometry, University of California, Berkeley, Berkeley, California, United States
  • Footnotes
    Commercial Relationships   Austin Roorda, C.Light Technologies (I), University of Rochester, University of Houston, USPTO#6,890,076 (P), University of Rochester, University of Houston, USPTO#7,118,216 (P)
  • Footnotes
    Support  NIH Grants R01-EY023591, U01-EY025501, P30-EY003176, K23-EY022412 F32-EY027637; Lowy Medical Research Institute; Foundation Fighting Blindness
Investigative Ophthalmology & Visual Science July 2018, Vol.59, 756. doi:
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      Austin Roorda; Functional properties of human retina measured with Adaptive Optics. Invest. Ophthalmol. Vis. Sci. 2018;59(9):756.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Presentation Description : Much of our knowledge about retinal function on a cellular scale has been learned from dissected preparations, which offer precise control over experimental conditions. To understand the next important step— how the signals that arise from retinal neurons are handled downstream by the brain — an in vivo approach is necessary. Fortunately, the optics of the eye afford a view of the retina that is only obscured by its optical imperfections. Recent advances in ocular imaging – namely adaptive optics and eye tracking - now make it possible to overcome these imperfections and not only image photoreceptors in a living eye, but to stimulate individual targeted cells with light. In my talk, I will describe this technology and how we are using it to reveal the neural circuitry that underlies human spatial and color vision and how it has new light on how to interpret images of patients with ocular disease.

This is an abstract that was submitted for the 2018 ARVO Annual Meeting, held in Honolulu, Hawaii, April 29 - May 3, 2018.

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