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Austin Roorda; Functional properties of human retina measured with Adaptive Optics. Invest. Ophthalmol. Vis. Sci. 2018;59(9):756.
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Presentation Description :
Much of our knowledge about retinal function on a cellular scale has been learned from dissected preparations, which offer precise control over experimental conditions. To understand the next important step— how the signals that arise from retinal neurons are handled downstream by the brain — an in vivo approach is necessary. Fortunately, the optics of the eye afford a view of the retina that is only obscured by its optical imperfections. Recent advances in ocular imaging – namely adaptive optics and eye tracking - now make it possible to overcome these imperfections and not only image photoreceptors in a living eye, but to stimulate individual targeted cells with light. In my talk, I will describe this technology and how we are using it to reveal the neural circuitry that underlies human spatial and color vision and how it has new light on how to interpret images of patients with ocular disease.
This is an abstract that was submitted for the 2018 ARVO Annual Meeting, held in Honolulu, Hawaii, April 29 - May 3, 2018.
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