July 2018
Volume 59, Issue 9
Open Access
ARVO Annual Meeting Abstract  |   July 2018
Assessment of Fluorescein Angiographic Pattern and Its prognostic value in Idiopathic Epiretinal Membrane
Author Affiliations & Notes
  • Ik Soo Byon
    Ophthalmology, Pusan National University Yangsan Hospital, Yangsan, Korea (the Republic of)
    Pusan National Univsersity School of Medicine, Yangsan, Korea (the Republic of)
  • Hanjo Kwon
    Pusan National Univsersity School of Medicine, Yangsan, Korea (the Republic of)
  • Sungwho Park
    Pusan National Univsersity School of Medicine, Yangsan, Korea (the Republic of)
  • Ji Eun E Lee
    Pusan National Univsersity School of Medicine, Yangsan, Korea (the Republic of)
  • Footnotes
    Commercial Relationships   Ik Soo Byon, None; Hanjo Kwon, None; Sungwho Park, None; Ji Eun Lee, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science July 2018, Vol.59, 842. doi:
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    • Get Citation

      Ik Soo Byon, Hanjo Kwon, Sungwho Park, Ji Eun E Lee; Assessment of Fluorescein Angiographic Pattern and Its prognostic value in Idiopathic Epiretinal Membrane
      . Invest. Ophthalmol. Vis. Sci. 2018;59(9):842.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To investigate a fluorescein angiographic pattern and its association with visual outcome in idiopathic epiretinal membrane (ERM) removal.

Methods : This study was nonrandomized, retrospective, comparative, interventional case series. Idiopathic ERM patients with visual acuity of 20/200 to 20/30, intact ellipsoid zone (EZ), and postoperative follow-up of 6 months were included. Fluorescein angiography (FA) was conducted at baseline. Optical coherence tomography (OCT) was assessed at baseline and follow-up visits. Baseline FA pattern in macula and changes in visual acuity (VA) and OCT findings after ERM removal were evaluated.

Results : Of total 46 eyes, 22 eyes (47.8 %) showed hyper-fluorescein of macula in mid-phase FA (Leak group). Their baseline parameters including VA and central macular thickness (CMT) were not different from eyes without leakage (Non-Leak group, n=24), except the inner retinal layer on fovea (IRLF) (11 vs 19, p= 0.004). The Leak group showed the worse VA (logMAR) (0.23 vs 0.12, p = 0.038) and thicker CMT (376.52 vs 316.39 μm, p = 0.007) at 6 months. Logistic regression analysis showed that the baseline FA pattern and VA were associated with final VA ≥ 20/25 (p = 0.028 and p = 0.019, respectively).

Conclusions : Approximately a half of idiopathic ERM patients showed a leakage of macula in FA. This FA pattern indicated the advanced damage in the inner retinal layers and provided a predictive value for visual prognosis after ERM removal.

This is an abstract that was submitted for the 2018 ARVO Annual Meeting, held in Honolulu, Hawaii, April 29 - May 3, 2018.

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