Abstract
Purpose :
In the treatment of Diabetic Macular Edema (DME), a multicenter retrospective registration survey of a 2-year treatment course in clinical practice has been conducted. Here, we report about a statistical analysis in terms of Visual Acuity (VA) from the viewpoint of comparing the year of starting interventional treatment.
Methods :
Based on clinical records, 1171 treatment näive DME eyes which had been started interventional treatment from 2010 to 2014 for 2 years at 18 domestic facilities were registered. The VA, Central Retinal Thickness (CRT) and the required number of each intervention (anti-VEGF drugs, corticosteroid, macula photocoagulation or vitrectomy) during the clinical course were extracted.
Results :
Interventional treatment for 247 eyes was started before 2011, 219 eyes in 2012, 331 eyes in 2013, 313 eyes in 2014. The improvement of VA was -0.058±0.364 log MAR, -0.037±0.343 log MAR, -0.043±0.376 log MAR, -0.082±0.352 log MAR. The number of eye treated by anti-VEGF drugs was 111 (44.9%), 145 (66.2%), 199 (60.1%), 248 (79.2%).
Conclusions :
From this real world data, the newer the year of starting interventional treatment, the better improvement of VA was obtained after a 2-year treatment course for DME in clinical practice. And the proportion of eyes treated by anti-VEGF injection has increased from year to year.
This is an abstract that was submitted for the 2018 ARVO Annual Meeting, held in Honolulu, Hawaii, April 29 - May 3, 2018.