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Nicola Cardascia, Gabriella La Tegola, Valentina Pastore, Vito Bini, Giovanni Alessio; Graft Detachment After Descemet Stripping Automated Endothelial keratoplasty. Invest. Ophthalmol. Vis. Sci. 2018;59(9):1302. doi: https://doi.org/.
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© ARVO (1962-2015); The Authors (2016-present)
To define Graft Detachment (GD)and Air Re-Bubbling (ARB) rates and surgical relevance after Descemet Stripping Automated Endothelial keratoplasty (DSAEK) in Bullous Keratopathy (BK) and Fuchs Endothelial Dystrophy (FED).
Retrospective study. One-hundred-four eyes affected by BK (59,56.73%) and FED (45,43.27%) underwent primary DSAEK between January 2016 and October 2017. Patients’ data and donor tissue characteristics were analyzed.
Eyes were scheduled for surgery for FED and BK within 12 and 14 months from visual impairment. Forty FED (88.89%) and 13 BK(22%) eyes received combined lens phacoemulsification, IOL implant. Tissues implanted in eyes affected by FED were younger (FED:61.69±10.26 y;BK: 65.68±8.66y;p0.05) and thinner (FED 665.89±61.34µ ;BK:778.89±196.04µ;p=0.03 ) than BK ones. Nine BK and 19 FED eyes underwent ARB (OR:0.25,p=0.003), within 8 and 5 days respectively. In BK GD was associated with unsuccessful cataract extraction (OR:7.83,p=0.04) and aphakia (OR:54.38,p=0.02). In FED it was slightly associated with aged patients (73.32±7.76years,p=0.07) and tissue explanted by patients affected by neoplasia (OR: 4.04,p=0.06).
GD can be easily recovered by ARB, restoring anatomical and functional outcomes. Surgeons have to be aware of aphakia and complicated cataract extraction in BK and probably of age and donor neoplasia in FED.
This is an abstract that was submitted for the 2018 ARVO Annual Meeting, held in Honolulu, Hawaii, April 29 - May 3, 2018.
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