July 2018
Volume 59, Issue 9
Open Access
ARVO Annual Meeting Abstract  |   July 2018
Five-year Clinical Results Comparing Descemet Stripping Automated Endothelial Keratoplasty and non Descemet Stripping Automated Endothelial Keratoplasty
Author Affiliations & Notes
  • Takashi Omoto
    University of Tokyo Hospital, Tokyo, Japan
    JR Tokyo General Hospital, Tokyo, Japan
  • Tetsuya Toyono
    University of Tokyo Hospital, Tokyo, Japan
  • Rika Shirakawa
    University of Tokyo Hospital, Tokyo, Japan
  • Junko Yoshida
    University of Tokyo Hospital, Tokyo, Japan
  • Takashi Miyai
    University of Tokyo Hospital, Tokyo, Japan
  • Satoru Yamagami
    Nihon University Hospital, Tokyo, Japan
  • Tomohiko Usui
    University of Tokyo Hospital, Tokyo, Japan
  • Footnotes
    Commercial Relationships   Takashi Omoto, None; Tetsuya Toyono, None; Rika Shirakawa, Chuo Sangio (F); Junko Yoshida, None; Takashi Miyai, Chuo Sangio (F), Konan Medical (F), KOWA (F), TOPCON (F); Satoru Yamagami, HOYA (F); Tomohiko Usui, Bonac (F), Senju (F)
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1306. doi:
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    • Get Citation

      Takashi Omoto, Tetsuya Toyono, Rika Shirakawa, Junko Yoshida, Takashi Miyai, Satoru Yamagami, Tomohiko Usui; Five-year Clinical Results Comparing Descemet Stripping Automated Endothelial Keratoplasty and non Descemet Stripping Automated Endothelial Keratoplasty. Invest. Ophthalmol. Vis. Sci. 2018;59(9):1306.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To compare 5-year clinical results of Descemet stripping automated endothelial keratoplasty (DSAEK) and non Descemet stripping automated endothelial keratoplasty (nDSAEK) in Japanese eyes.

Methods : A retrospective chart review was performed on patients who underwent DSAEK or nDSAEK 5 years ago. We performed comparative analysis on demographics, best corrected visual acuity (BCVA), endothelial cell density (ECD), graft survival rate and complications.

Results : Fifty-three eyes (DSAEK 28, nDSAEK 25) of 48 patients were included in this study. The common indications for DSAEK and nDSAEK were bullous keratopathy due to ophthalmic procedures in 21 eyes (DSAEK 8, nDSAEK 13) and Fuchs endothelial dystrophy in 12 (DSAEK 9, nDSAEK3). The preoperative BCVA of DSAEK and nDSAEK were 1.18 and 1.11 log MAR, which improved to 0.33 and 0.23, 0.13 and 0.17, and 0.19 and 0.14 at 1, 3 and 5 years, respectively. The donor ECD of DSAEK and nDSAEK were 2615 and 2574, which decreased to 1585 and 1611, 1104 and 1511, and 1119 and 1063 at 1, 3 and 5 years, respectively. The graft survival rate of DSAEK and nDSAEK were 0.93 and 0.83, 0.83 and 0.75, and 0.64 and 0.70 at 1, 3 and 5 years, respectively. The common complications were graft detachment (DSAEK5, nDSAEK3), IOP elevation (DSAEK5, nDSAEK2), primary graft failure (DSAEK 2, nDSAEK 3) and macular edema (DSAEK1, nDSAEK4). There was not a statically significant difference between DSAEK and nDSAEK in BCVA, ECD, graft survival rate and complications.

Conclusions : Our 5-year clinical results of DSAEK and nDSAEK showed similar outcomes in BCVA, ECD, graft survival rate and complications.

This is an abstract that was submitted for the 2018 ARVO Annual Meeting, held in Honolulu, Hawaii, April 29 - May 3, 2018.

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