Abstract
Purpose :
To compare 5-year clinical results of Descemet stripping automated endothelial keratoplasty (DSAEK) and non Descemet stripping automated endothelial keratoplasty (nDSAEK) in Japanese eyes.
Methods :
A retrospective chart review was performed on patients who underwent DSAEK or nDSAEK 5 years ago. We performed comparative analysis on demographics, best corrected visual acuity (BCVA), endothelial cell density (ECD), graft survival rate and complications.
Results :
Fifty-three eyes (DSAEK 28, nDSAEK 25) of 48 patients were included in this study. The common indications for DSAEK and nDSAEK were bullous keratopathy due to ophthalmic procedures in 21 eyes (DSAEK 8, nDSAEK 13) and Fuchs endothelial dystrophy in 12 (DSAEK 9, nDSAEK3). The preoperative BCVA of DSAEK and nDSAEK were 1.18 and 1.11 log MAR, which improved to 0.33 and 0.23, 0.13 and 0.17, and 0.19 and 0.14 at 1, 3 and 5 years, respectively. The donor ECD of DSAEK and nDSAEK were 2615 and 2574, which decreased to 1585 and 1611, 1104 and 1511, and 1119 and 1063 at 1, 3 and 5 years, respectively. The graft survival rate of DSAEK and nDSAEK were 0.93 and 0.83, 0.83 and 0.75, and 0.64 and 0.70 at 1, 3 and 5 years, respectively. The common complications were graft detachment (DSAEK5, nDSAEK3), IOP elevation (DSAEK5, nDSAEK2), primary graft failure (DSAEK 2, nDSAEK 3) and macular edema (DSAEK1, nDSAEK4). There was not a statically significant difference between DSAEK and nDSAEK in BCVA, ECD, graft survival rate and complications.
Conclusions :
Our 5-year clinical results of DSAEK and nDSAEK showed similar outcomes in BCVA, ECD, graft survival rate and complications.
This is an abstract that was submitted for the 2018 ARVO Annual Meeting, held in Honolulu, Hawaii, April 29 - May 3, 2018.