July 2018
Volume 59, Issue 9
Open Access
ARVO Annual Meeting Abstract  |   July 2018
De novo iris abnormality after Descemet membrane endothelial keratoplasty and its impact on postoperative clinical outcomes
Author Affiliations & Notes
  • Hideaki Yokogawa
    Ophthalmology, Kanazawa University School of Medicine, Kanazawa-shi, Ishikawa-ken, Japan
  • Akira Kobayashi
    Ophthalmology, Kanazawa University School of Medicine, Kanazawa-shi, Ishikawa-ken, Japan
  • Natsuko Mori
    Ophthalmology, Kanazawa University School of Medicine, Kanazawa-shi, Ishikawa-ken, Japan
  • Tsubasa Nishino
    Ophthalmology, Kanazawa University School of Medicine, Kanazawa-shi, Ishikawa-ken, Japan
  • Toshinori Masaki
    Ophthalmology, Kanazawa University School of Medicine, Kanazawa-shi, Ishikawa-ken, Japan
  • Kazuhisa Sugiyama
    Ophthalmology, Kanazawa University School of Medicine, Kanazawa-shi, Ishikawa-ken, Japan
  • Footnotes
    Commercial Relationships   Hideaki Yokogawa, None; Akira Kobayashi, None; Natsuko Mori, None; Tsubasa Nishino, None; Toshinori Masaki, None; Kazuhisa Sugiyama, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1310. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      Hideaki Yokogawa, Akira Kobayashi, Natsuko Mori, Tsubasa Nishino, Toshinori Masaki, Kazuhisa Sugiyama; De novo iris abnormality after Descemet membrane endothelial keratoplasty and its impact on postoperative clinical outcomes. Invest. Ophthalmol. Vis. Sci. 2018;59(9):1310.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Purpose : The purpose of this study is to elucidate the frequency of de novo iris abnormality after Descemet membrane endothelial keratoplasty (DMEK) and its impact on postoperative clinical outcomes.

Methods : In this retrospective case series, medical records of consecutive 32 eyes of 28 patients (mean age, 65.7 ± 13.4 year, 14 men, 18 women) who underwent DMEK (or triple DMEK) in our hospital was reviewed. In all patients, inferior peripheral iridectomy was created leaving full intracameral air tamponade at the end of surgery. SF6 gas was not used in any cases. De novo iris abnormality such as pupillary shape change and iris depigmentation was evaluated by 3 independent observers in a masked fashion. Pre-existing iris abnormality was excluded. Eyes were divided into two groups based on presence of these de novo iris changes; Group A (with iris abnormality) and Group B (no iris abnormality). Impact on postoperative clinical outcomes such as visual outcomes and endothelial cell density between two groups were analyzed.

Results : De novo iris abnormality was seen in 15 eyes (9 eyes with pupillary shape change and 6 eyes with iris depigmentation, =group A, 46.9%), and were not seen in 17 eyes (=Group B, 53.1%). No differences were detected between Group A and Group B, in age (p = 0.60), sex (p = 0.31), indication (p = 0.13), simultaneous cataract surgery (p = 0.40), pre- and 6 months postoperative vision (p = 0.11 and 0.78), donor age (p = 0.52), and donor and 6 months postoperative endothelial cell density (p = 0.66 and 0.54).

Conclusions : De novo iris abnormality was noted in almost half number of eyes after DMEK (46.9%). However, visual outcomes and postoperative endothelial cell density were not affected by these iris changes at least 6 months postoperatively.

This is an abstract that was submitted for the 2018 ARVO Annual Meeting, held in Honolulu, Hawaii, April 29 - May 3, 2018.

×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×