July 2018
Volume 59, Issue 9
Open Access
ARVO Annual Meeting Abstract  |   July 2018
Efficacy of Tectonic Graft using preserved human scleral tissue after Proper
Antifungal Treatment in Fungal Necrotizing Sclerokeratitis
Author Affiliations & Notes
  • Hyung-Joon Kim
    Department of Ophthalmology, Daegu Catholic Univ Hospital, Daegu, Korea (the Democratic People's Republic of)
  • He Ri Kang
    Department of Ophthalmology, Daegu Catholic Univ Hospital, Daegu, Korea (the Democratic People's Republic of)
  • SI DONG KIM
    Department of Ophthalmology, Daegu Catholic Univ Hospital, Daegu, Korea (the Democratic People's Republic of)
Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1324. doi:
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      Hyung-Joon Kim, He Ri Kang, SI DONG KIM; Efficacy of Tectonic Graft using preserved human scleral tissue after Proper
      Antifungal Treatment in Fungal Necrotizing Sclerokeratitis
      . Invest. Ophthalmol. Vis. Sci. 2018;59(9):1324.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To investigate the effect of tectonic graft using preserved human scleral tissue after proper antifungal treatment in fungal necrotizing sclerokeratitis

Methods : 6 eyes with intractable fungal necrotizing sclerokeratitis which had occurred after pterygium removal were surgically treated with urgent tectonic graft using preserved human scleral tissue after proper treatment with antifungal agents. Subsequent penetrating keratoplasty were performed in 2 eyes and evaluated more than 24 months

Results : After 4 weeks of antifungal treatments, sclerocorneal lesions were stabilized in 5 eyes, and repetitive fungus smear test confirmed negative findings. Therapeutic tectonic scleral graft was performed, and a graft melting was developed secondary to delayed epithelial healing in one eye. In two eyes with severe corneal infiltration, subsequent penetrating keratoplasty were performed and no rejection was developed during the follow-up period of more than 24 months.

Conclusions : This study showed that tectonic graft using preserved human scleral tissue with proper antifungal therapy is a useful method for the treatment of fungal necrotizing sclerokeratitis. When treating patients with fungal necrotizing sclerokeratitis, preoperative antifungal therapy and confirmation of negative findings in repetitive fungus smear test are important.

This is an abstract that was submitted for the 2018 ARVO Annual Meeting, held in Honolulu, Hawaii, April 29 - May 3, 2018.

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