July 2018
Volume 59, Issue 9
Open Access
ARVO Annual Meeting Abstract  |   July 2018
Changing Trends of Original Diseases and Surgical Procedures in Corneal Transplantation
Author Affiliations & Notes
  • Aya Takahashi
    Opthhalmology, Tokyo Dental College Ichikawa, Ichikawa, Japan
  • Yuriko Takahashi
    Opthhalmology, Tokyo Dental College Ichikawa, Ichikawa, Japan
  • Chiaki Sasaki
    Opthhalmology, Tokyo Dental College Ichikawa, Ichikawa, Japan
  • Sota Nishisako
    Opthhalmology, Tokyo Dental College Ichikawa, Ichikawa, Japan
  • Jun Shimazaki
    Opthhalmology, Tokyo Dental College Ichikawa, Ichikawa, Japan
  • Footnotes
    Commercial Relationships   Aya Takahashi, None; Yuriko Takahashi, None; Chiaki Sasaki, None; Sota Nishisako, None; Jun Shimazaki, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1327. doi:
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      Aya Takahashi, Yuriko Takahashi, Chiaki Sasaki, Sota Nishisako, Jun Shimazaki; Changing Trends of Original Diseases and Surgical Procedures in Corneal Transplantation. Invest. Ophthalmol. Vis. Sci. 2018;59(9):1327.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : The aim of our study is to report the changing trends of original diseases and surgical procedures in corneal transplantation conducted in a tertiary referral hospital located in the Tokyo Metroporitan area over the last 23 years.

Methods : We retrospectively reviewed the medical records of 5001 cases underwent corneal transplantation from January 1991 to July 2014 at our hospital. We divided the time periods into 3 groups; from 1991 to 1998 (Period 1, n = 1252), from 1999 to 2006 (Period 2, n = 2231), and from 2007 to 2014 (Period 3, n = 1518). We examined the incidence of original diseases and surgical procedures in the three study periods.

Results : The incidence of bullous keratopathy (BK) showed an increasing trend with 22.5%, 30.0% and 44.3% in the Periods 1, 2, and 3, respectively. While the incidence of regrafting were similar among the time periods (18.5%, 22.1%, and 21.9%), that of corneal scar showed a decreasing trend (24.7%, 22.1%, and 7.6%). As surgical procedures, incidence of penetrating keratoplasty (PKP) has been decreasing especially in the Period 3 (80.3%, 83.4%, and 53.2%). Deep anterior lamellar keratoplasty (DALK) and endothelial keratoplasty (EK, mostly Descemet’s stripping endothelial keratoplasty) have been increasing (1.8%, 8.2%, and 11.5% in DALK, and 0.17%, 2.4%, and 32.4% in EK). The proportions of PKP for either BK or keratoconus have been decreasing (100%, 96.2%, and 41.0% in BK, and 97.8%,80.9%, and 49.6% in keratoconus), reflecting changing trends shifting from PKP to either DALK or EK.

Conclusions : The incidence of component lamellar keratoplasty such as DALK and EK showed dramatical increases, especially in the last decade.

This is an abstract that was submitted for the 2018 ARVO Annual Meeting, held in Honolulu, Hawaii, April 29 - May 3, 2018.

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