Abstract
Purpose :
To study the efficacy and safety of amniotic membrane transplantation as an adjunctive therapy after surgical excision of primary pterygium and compare the clinical outcomes with limbal-conjunctival autograft.
Methods :
Prospective Randomized Blind Clinical Trial
Sixty-one eyes of 57 patients with primary nasal pterygium have been operated by two surgeons (E. G-H, A. N-C). All patients are randomized to undergo Mini-SLET or limbal-conjunctival autograft transplantation as an adjuvant therapy after pterygium excision.
Four eyes were treated with Mini-SLET(group 1), and 26 eyes have been operated with limbal-conjunctival autograft (LCA) (group 2). Patients will be followed up at 1 day, 1 week, 1, 3, 6, 9 and 12 months postoperation. The main outcome measurement was a recurrence rate after surgery.
Results :
There were no differences between both groups in terms of gender distribution, age and petrygium size. The mean follow-up was 12.0 months in both groups. There were 18 recurrences (50%) in the Mini-Slet group and three (9.09%) in the LCA group, which was significantly different among both groups (P < 0.05).
Conclusions :
The surgical results of primary pterygium excision followed by Mini-Slet versus limbal-conjunctival autograft transplantation were compared. It was found that Mini-Slet treatmen for pterygium surgery has an unacceptably high recurrence rate.
This is an abstract that was submitted for the 2018 ARVO Annual Meeting, held in Honolulu, Hawaii, April 29 - May 3, 2018.