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Seung Mo Kim, Joo Young Kwag, Hungwon Tchah, Jae Yong Kim; Subtenon Triamcinolone Injection Can Prevent Post-Penetrating Keratoplasty Rejection. Invest. Ophthalmol. Vis. Sci. 2018;59(9):1348.
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© ARVO (1962-2015); The Authors (2016-present)
To investigate the effects of postoperative subtenon TA injection (sTA) on the graft rejection after Penetrating Keratoplasty (PK).
Between 2009 and 2015, 119 eyes out of 89 patients who underwent PK were included. 102 eyes received sTA every three months postoperatively, but 17 eyes did not. The visual acuity, IOP, and refraction were checked at each visits.The mean follow-up period were 12 months postoperatively.
The Kaplan-Meier survival analysis showed that the sTA group showed less graft rejection than the non-injection group (p=0.02). The logistic regression analyses revealed that pre-PK glaucoma surgery history was predictive for graft rejection, but multiple post-PK sTA was protective (p<0.05). However, there were temporary IOP elevation and epithelial defect cases.
The post-PK sTA could prevent graft rejection in spite of minor complications
This is an abstract that was submitted for the 2018 ARVO Annual Meeting, held in Honolulu, Hawaii, April 29 - May 3, 2018.
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