July 2018
Volume 59, Issue 9
Open Access
ARVO Annual Meeting Abstract  |   July 2018
Comparison of changes in corneal biomechanical properties after uneventful phacoemulsification in diabetic and non-diabetic patients

Author Affiliations & Notes
  • Angela M Carneiro
    Faculty Medicine Porto, Hospital Sao Joao, Porto, Portugal
    Ophthalmology, Hospital Sao Joao, Porto, Portugal
  • Joao N Beato
    Faculty Medicine Porto, Hospital Sao Joao, Porto, Portugal
    Ophthalmology, Hospital Sao Joao, Porto, Portugal
  • Jo?o Esteves
    Ophthalmology, Hospital Sao Joao, Porto, Portugal
  • David Reis
    Faculty Medicine Porto, Hospital Sao Joao, Porto, Portugal
  • Manuel Falcao
    Faculty Medicine Porto, Hospital Sao Joao, Porto, Portugal
    Ophthalmology, Hospital Sao Joao, Porto, Portugal
  • Vitor Rosas
    Ophthalmology, Hospital Sao Joao, Porto, Portugal
  • Fernando Falcao-Reis
    Faculty Medicine Porto, Hospital Sao Joao, Porto, Portugal
    Ophthalmology, Hospital Sao Joao, Porto, Portugal
  • Footnotes
    Commercial Relationships   Angela Carneiro, None; Joao Beato, None; Jo?o Esteves, None; David Reis, None; Manuel Falcao, None; Vitor Rosas, None; Fernando Falcao-Reis, None
  • Footnotes
    Support  none
Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1405. doi:
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    • Get Citation

      Angela M Carneiro, Joao N Beato, Jo?o Esteves, David Reis, Manuel Falcao, Vitor Rosas, Fernando Falcao-Reis; Comparison of changes in corneal biomechanical properties after uneventful phacoemulsification in diabetic and non-diabetic patients

      . Invest. Ophthalmol. Vis. Sci. 2018;59(9):1405.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To compare corneal biomechanical changes after uneventful phacoemulsification cataract surgery between type 2 diabetic (DM) and non-diabetic patients.

Methods : Forty-four diabetic (44 eyes) and 44 (44 eyes) age and sex-matched non-DM controls with age-related cataract were enrolled in this prospective observational study. Corneal hysteresis (CH), corneal resistance factor (CRF) and corneal-compensated intraocular pressure (IOPcc) were evaluated using the Ocular Response Analyzer® (ORA); central corneal thickness (CCT) was recorded using the Pentacam HR. Patients were evaluated preoperatively and 1 and 6 months after surgery.

Results : In both groups, there was a significant postoperative IOPcc reduction 6 months after surgery (p<0.001), however, CCT was not found to significantly change in the postoperative period. In the DM group, CH was observed to be significantly lower than preoperative value at 1 month (p=0.040) but not at 6 months follow-up (p=0.437); while it did not change significantly in the non-DM group (p=0.376 and p=0.135, respectively). CRF was significantly lower at 1 and 6 months than the preoperative values. Multivariate linear regression showed that greater preoperative IOPcc (p<0.001), shorter axial length (p<0.001) and male gender (p=0.005) were significantly associated with greater IOPcc decrease after 6 months. Postoperative CH change was significantly associated with preoperative CH (p<0.001), preoperative IOPcc (0.004) and IOPcc change (p<0.001); whereas CRF change was only correlated with preoperative CRF (p<0.001).

Conclusions : This study shows comparable corneal biomechanical changes between DM and non-DM groups, and suggest that CH and CRF respond differently to cataract surgery.

This is an abstract that was submitted for the 2018 ARVO Annual Meeting, held in Honolulu, Hawaii, April 29 - May 3, 2018.

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