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Laura Cañola, Juan Carlos Izquierdo, Luis Izquierdo, Carmen Maldonado, Maria Henriquez; Corneal Tomographic Findings in Patients with Glaucoma and Abnormal Corneas. Invest. Ophthalmol. Vis. Sci. 2018;59(9):2021. doi: https://doi.org/.
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© ARVO (1962-2015); The Authors (2016-present)
To evaluate tomographic parameters from Scheimpflug analysis in patients diagnosed with glaucoma and abnormal cornea.
Cross-sectional retrospective case series study that included 36 eyes of 18 patients, with glaucoma diagnosis at Institute of Eyes, Oftalmosalud, Lima, Peru, between January 2012 and December 2012 and presented abnormal corneas from Scheimpflug analysis. All patients underwent SD-OCT (Spectral Domain Optical Coherence Tomography; Carl Ziess Meditec, Dublin, CA), HRT (Heidelberg Retina Tomograph; Heidelberg Engineering GmbH, Heidelberg, Germany), CV (Visual Field; Humphreys Visual Field Analyzer, Carl Ziess Meditec, Dublin, CA) and Pentacam (Oculus Inc, Wetzlar, Germany); also, we evaluated visual acuity without correction (AVSC) and intraocular pressure. Abnormal cornea was defined if the cornea meet 3 or more of the suggested cutoff values for subclinical keratoconus. The statistical analysis was performed with SPSS Statistics Version 20.
18 patients with an age range between 34.0 to 74.0 years (58.00±12.78) were diagnosed with glaucoma. Mean BCVA was 0.39±0.64 LogMAR and mean IOP was 15.11±2.8. Mean OCT relation cup/disc was 0.67±0.13. Mean HRT area C / D was 0.45± 0.13, mean ring area was 1.56± 0.50, mean RNFL was 0.23± 0.16 and in the classification Moorfields was 9 (25%) eyes were reported as Borderline and 27 (75%) as Normal. Mean Visual Field the MD was -3.68±3.96. In the analysis Scheimfplflug mean pachymetry at the thinnest point was 559.69±33.92, mean Kmax was 5.22± 2.67, mean K1 Later was -6.13± 0.20 and mean K2 Later was -6.58± 0.37. 11.11% of the eyes had more than 3 parameters considerer for subclinical keratoconus, 8.33% had more than 5 and 8.33% had more than 6. 13.88% of the eyes had more than 3 parameters considerer for keratoconus, 8.33% had more than 5 and 8.33% had more than 6.
This study demonstrates for the first time, evidence between glaucoma and topographic abnormal corneas. Further longitudinal, prospective study are necessary to evaluate the prevalence of this find in glaucoma patients.
This is an abstract that was submitted for the 2018 ARVO Annual Meeting, held in Honolulu, Hawaii, April 29 - May 3, 2018.
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