July 2018
Volume 59, Issue 9
Open Access
ARVO Annual Meeting Abstract  |   July 2018
Comparison of mean optic disc cup surface depth between glaucoma suspect and primary open-angle glaucoma with large cup-to-disc ratio
Author Affiliations & Notes
  • Yongseok Mun
    Ophthalmology, Seoul National University Hospital, Seoul, Seongbuk-gu, Korea (the Republic of)
  • Ah Nul Ha
    Ophthalmology, Seoul National University Hospital, Seoul, Seongbuk-gu, Korea (the Republic of)
  • Jin Wook Jeoung
    Ophthalmology, Seoul National University Hospital, Seoul, Seongbuk-gu, Korea (the Republic of)
  • Ki Ho Park
    Ophthalmology, Seoul National University Hospital, Seoul, Seongbuk-gu, Korea (the Republic of)
  • Young Kook Kim
    Ophthalmology, Seoul National University Hospital, Seoul, Seongbuk-gu, Korea (the Republic of)
  • Footnotes
    Commercial Relationships   Yongseok Mun, None; Ah Nul Ha, None; Jin Wook Jeoung, None; Ki Ho Park, None; Young Kook Kim, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science July 2018, Vol.59, 2098. doi:
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      Yongseok Mun, Ah Nul Ha, Jin Wook Jeoung, Ki Ho Park, Young Kook Kim; Comparison of mean optic disc cup surface depth between glaucoma suspect and primary open-angle glaucoma with large cup-to-disc ratio. Invest. Ophthalmol. Vis. Sci. 2018;59(9):2098.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : Optic nerve head surface depression in patients with glaucoma was previously reported. We compared mean optic disc cup surface depth between glaucoma-like disc with large cup-to-disc ratio and primary open-angle glaucoma (POAG) eyes.

Methods : Total 40 eyes of 40 patients with glaucoma-like disc and 40 eyes of 40 patients with POAG were included in this study. All patients had an average cup-to-disc ratio between 0.7 and 0.8. The optic disc area, mean cup-to-disc ratio and mean optic disc cup volume were measured using Spectral-domain optical coherence tomography (Cirrus™ HD-OCT). The mean optic disc cup surface depth was calculated using the following formula: [mean optic disc cup volume / (optic disc area x (mean cup-to-disc ratio^2))] - 200µm.

Results : The mean optic disc cup surface depth were 134.54±66.15 and 207.48±86.47 µm in glaucoma-like disc and POAG group, respectively, and the difference between two groups was statistically significant (p<0.001, t-test).

Conclusions : Patients with POAG showed significantly greater mean optic disc cup surface depth compared to glaucoma-like disc with similar mean cup-to-disc ratio. The mean optic disc cup surface depth may provide additional information in diagnosis and evaluation of POAG. In addition, considering the fact that depression of optic nerve head can occur prior to the retinal nerve fiber layer defect, mean optic disc cup surface depth is expected to be an another early diagnosis index for POAG.

This is an abstract that was submitted for the 2018 ARVO Annual Meeting, held in Honolulu, Hawaii, April 29 - May 3, 2018.

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