Abstract
Purpose :
To measure the influence of cataract surgically induced intraocular pressure fluctuating on peripapillary and macular vessel density in patients using optical coherence tomography angiography.
Methods :
Fifty-two eyes of 52 patients with cataract for cataract surgery were enrolled prospectively. IOP was measured by a non-contacttonometer and Peripapillary and Macular Vessel Density was measured by OCTA at preoperative and postoperative minutes 0 and 60 and hours 8 and 24.
Results :
Compared with preoperative, intraocular pressure in the normal range at 0 minutes, 60 minutes postoperative, the difference was not statistically significant. But the perfusion density of macular at postoperative 0 min and postoperative 60min were reduced than preoperative，and it recovered between1hour and 2hour . The vascular density of macular at postoperative 0 min were reduced than preoperative，and it recovered at postoperative 60 min. At 8 and 24 hours postoperative, peripapillary and macular vessel density did not change than preoperative when the intraocular pressure lower than 40 mmHg. The peripapillary and macular vessel density were reduced than preoperative when the intraocular pressure higher than 40 mmHg.
Conclusions :
Fundus vessel density reduced result from the intraoperative perfusion pressure, the perfusion density of macular was still not fully recovered after 60 minutes. It can lead to the reduction of the fundus vessel density when the intraocular pressure higher than 40 mmHg. We should pay close attention to intraoperative and postoperative intraocular pressure on the impact of peripapillary and macular vessel density, in avoid of fundus ischemic injury.
This is an abstract that was submitted for the 2018 ARVO Annual Meeting, held in Honolulu, Hawaii, April 29 - May 3, 2018.