Abstract
Purpose :
To investigate the predictive factors of visual acuity after cataract surgery in patients with retinitis pigmentosa (RP).
Methods :
The changes in best-corrected visual acuity (BCVA) before and 3 months after surgery were measured. The relation between preoperative ellipsoid zone (EZ) conditions, external limiting membrane (ELM) conditions, central macular thickness (CMT) and postoperative BCVA were investigated. A multiple linear regression analysis was then performed using the preoperative BCVA, status of EZ, status of ELM and CMT as variables to evaluate the impact on postoperative VA.
Main Outcome Measures: The status of EZ, ELM and CMT measured by optical coherence tomography (OCT), the preoperative and postoperative BCVA.
Results :
The mean BCVA significantly improved after cataract surgery from 0.80 (range, 0.05 to 2.40) to 0.45 (range, 0.00 to 2.40) (P < 0.001). However, final BCVA did not improve in 57 eyes (52.3%). The mean postoperative BCVA was significantly better in eyes with an intact ELM than those without (P < 0.001), also in eyes with an intact EZ than those without (P < 0.001) ,and in eyes with relatively normal CMT (>=200um) than those with decreased CMT (<200um) (P < 0.001). In multiple linear regression analysis, preoperative logMAR visual acuity (P<0.001), ELM integrity(P<0.001), and CMT(P=0.017) remained the only three variables that associated significiantly with postoperative BCVA (R2=0.753, p<0.001).
Conclusions :
Postoperative BCVA in approximately half of the eyes improved 3 months after cataract surgery in patients with RP. The preoperative BCVA, the status of ELM and CMT are important parameters to predict postoperative visual acuity.
This is an abstract that was submitted for the 2018 ARVO Annual Meeting, held in Honolulu, Hawaii, April 29 - May 3, 2018.