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Maximilian Wintergerst, Michael Petrak, Petra Larsen, Jeany Li, Frank Holz, Robert Patrick Finger, Tim U Krohne; Non-contact smartphone-based fundus photography in retinopathy of prematurity. Invest. Ophthalmol. Vis. Sci. 2018;59(9):2777.
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© ARVO (1962-2015); The Authors (2016-present)
To compare state-of-the-art contact fundus photography with a novel non-contact smartphone-based fundus photography device for documentation and evaluation of retinopathy of prematurity (ROP).
Twenty infants (23 eyes) with ROP were dilated and imaged both with Paxos Scope (Digisight Technologies Inc.) and RetCam Shuttle (Natus Medical Inc.). Fundus images were evaluated for image quality, field of view, presence and severity of plus disease, and ROP stage by three blinded graders (MW, PL, JL). In cases of uncertainty a senior grader (TK) was consulted. Data were analyzed descriptively.
Image quality was comparable between both devices. Details of ROP (e.g. extraretinal fibrovascular proliferations) could be visualized with Paxos Scope with a higher degree of image magnification. However, field of view was greater in RetCam imaging (ratio of diameters and areas 2.1:1 and 5:1, respectively) allowing for a better overview and orientation. Likewise, the retinal periphery could be visualized more easily with the RetCam. Sensitivity and specificity to detect plus disease were 96% and 100%, respectively. Evaluation of ROP stage was possible using the Paxos Scope and consistent with classification on RetCam imaging (weighted kappa: 0.71).
Smartphone-based fundus photography using Paxos Scope represents a promising novel tool for ROP documentation and evaluation, providing non-contact imaging with a quality comparable to conventional contact imaging devices.
This is an abstract that was submitted for the 2018 ARVO Annual Meeting, held in Honolulu, Hawaii, April 29 - May 3, 2018.
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