Detection of retinal microcirculation changes with angio OCT in haemodialised patients

Abstract

Purpose : To show if the haemodyalisis has any effect on the microcirculation of the eye, including especially macular flow and no-flow areas.

Methods : The examinations were performed from 2017 July to September in the Department of Ophthalmology of Markhot Ferenc Hospital and in the Fresenius MedicalCare Dialysis Center Eger, Hungary.
33 haemodialised patients underwent angio OCT examination, The average age was 62,48±14,27 years.We examined the patients with Optivue angio OCT. We detected the angioOCT values before (G1) and after(G2) the haemodyalis by follow up method. ANOVA analysis were performed on the datas.

Results :
The non-flow area was 0,47±0,49 mm² in G1,and 0,27±0,11 mm² in G2, the flow area in the Outer Retinal layer was 1,04±0,21 mm²in G1,and 1,05±0,21 mm² in G2. The flow area in the Chorioidal Capillary layer was 1,85±0,15 mm²in G1,and 1,86±0,1 mm² in G2. We can not detect any significant difference with ANOVA analysis between G1 and G2.
With ANOVA analysis we found in the parafoveal region significant difference between the pre and post haemodyalisis group with respect of flow density %.(51,25 ±5,3 % in G1) and (49,8± 4,1 %in G2) p=0,02

Conclusions : The modern angio OCT instruments makes the difference in the observation of the ocular blood flow. The results are detectable, archiveable, and give the possibility to make an exact follow up examination, and minimize the subjectivity of the examination.

This is an abstract that was submitted for the 2018 ARVO Annual Meeting, held in Honolulu, Hawaii, April 29 - May 3, 2018.