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DALILA RODRIGUEZ, ABEL Ramírez; Functional and structural findings measured by microperimetry and autofluorescence between wet and dry macular age related. Invest. Ophthalmol. Vis. Sci. 2018;59(9):3212.
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© ARVO (1962-2015); The Authors (2016-present)
To describe the characteristics of autofluorescense and microperimetry in patients with dry and wet macular age related.
We performed a descriptive, transversal study, in the department of Vitreous and Retina in Fundacion Hospital Nuestra Señora de la Luz, from April to September 2016, we recluted patients with dry and wet macular age related diagnosis, who wanted to participed, and signed the informed consent.
As results 22 patients were recruited, 44 eyes of which, mean age: 72 years, Female correspond 72.7% (16), male: 18.18% (4), visual acuity: 20/138. Regarding the type of AMD, 16 (36.36%) corresponded to the dry variety and 28 (63.63%) to the wet AMD. Autofluorescence patterns were for dry AMD (16): Focal: 7 (43.75), Diffuse: 1 (6.25%), Patch: 2 (12.5%), Reticular: 2 (12.5%), Band: 2 (12.5%) ), Granular: 2 (12.5%). For the wet variant (28) the patterns were: Granular: 15 (81.57%), Diffuse: 6 (21.42%), Band: 5 (17.85%), Patch: 1 (3.57%), Focal: 1 (3.57%)In relation to the retinal sensitivity these were the results for dry AMD (16) :, Sensitivity: 14.57 ± 0.3, Fixation Patterns: Stable: 10 (62.5%), Relatively unstable: 5 (31.25%), Unstable: 1 (6.25 %). Location: Central: 14 (87.5), Poorly central: 2 (12.5%), Eccentric: 0. For the case of wet AMD (28): Sensitivity: 12.922 ± 0.6; Fixation Patterns: Stable: 2 (7.14%) Relatively unstable: 6 (21.42%), Unstable: 20 (71.42%). The location: Central: 0, Poorly central: 5 (17.85%), Eccentric: 23 (82.14%)
As it is observed the determination of AV in macular alterations, especially in AMD, it is not sufficient to functionally assess vision. Microperimetry allows the evaluation of macular function quantitatively, as well as detecting the location and stability of retinal fixation. Midena et al., Compared the findings of microperimetry and autofluorescence in 13 eyes of patients with early AMD. They suggest the use of microperimetry and autofluorescence together to monitor the progression of AMD. As conclusions we have that the evaluation of the retinal sensitivity through microperimetry through the MAIA platform is a non-invasive, fast and safe diagnostic method. It is effective for the detection of the loss of early macular function in patients with AMD. It allows to quantify the threshold of the retinal sensitivity as well as the characteristics of the scotoma
This is an abstract that was submitted for the 2018 ARVO Annual Meeting, held in Honolulu, Hawaii, April 29 - May 3, 2018.
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