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Gyulli Kazakbaeva, Guzel Bikbova, Rinat Fayzrakhmanov, Yulia Uzyanbaeva, Rinat Zainullin, Jost B Jonas; Axial length and its associations in a Russian population: The Ural Eye and Medical Study.. Invest. Ophthalmol. Vis. Sci. 2018;59(9):3373. doi: https://doi.org/.
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© ARVO (1962-2015); The Authors (2016-present)
To assess the normal distribution of axial length and its associations in a Russian population.
The population-based Ural Eye and Medical Study was carried out in a rural and an urban area in the region of Ufa / Bashkortostan 1400 km East of Moscow. Out of 7328 eligible individuals aged 40+ years, 5,899 (80.5%) individuals participated and underwent an ocular and general examination. Axial length was measured sonographically.
Biometric data were available for 5709 (96.8%) individuals. Mean axial length was 23.33 ± 1.10 mm (median: 23.23 mm; range: 19.78-32.87mm) for the right eyes and 23.29 ± 1.09 mm (median: 23.19mm; range: 19.02-32.20mm) for left eyes. The 95% confidence interval (CI) ranged from 21.40mm to 25.91mm. Prevalences of any myopia (defined by axial length ≥24.0mm), minor myopia (axial length:24.0 to <24.50mm), moderate myopia (axial length:24.5 to <26.5mm), and high myopia (axial length >26.5mm) were 1232/5709 or 21.6% (95% confidence interval (CI): 20.5,22.7), 598/5709 or 10.5% (95%CI:9.7,11.3), 556/5709 or 0.7% (95%CI:9.0,10.5), 78/5709 or 1.4% (95%CI:1.1,1.7), respectively. In multivariate regression analysis, longer axial length was associated with higher level of education (P<0.001; standardized regression coefficient beta: 0.07; non-standardized regression coefficient B: 0.04; 95%CI:0.03,0.06), urban region of habitation (P=0.001;beta:-0.04;B:-0.09;95%CI:-0.15,-0.04), taller body height (P<0.001;beta:0.12;B:0.01;95%CI:0.01,0.02), thinner lens thickness (P<0.001;beta:-0.07;B:-0.18;95%CI:-0.24,-0.12), lower corneal refractive power (P<0.001;beta:-0.38;B:-0.23;95%CI:-0.24,-0.21), and higher intraocular pressure (P<0.001;beta:0.06;B:0.02;95%CI:0.01,0.02).
The prevalence of axial myopia, in particular of high axial myopia, is markedly lower in the Russian population than in East Asian populations. As in other ethnic groups, longer axial length was correlated with higher level of education, urban region of habitation, taller body height and higher intraocular pressure.
This is an abstract that was submitted for the 2018 ARVO Annual Meeting, held in Honolulu, Hawaii, April 29 - May 3, 2018.
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