July 2018
Volume 59, Issue 9
Open Access
ARVO Annual Meeting Abstract  |   July 2018
Anxiety, Depression and Vision- Related Quality of Life in Patients with Retinitis Pigmentosa.
Author Affiliations & Notes
  • Mayumi Sainohira
    Kagoshima Univerrsity, KAGOSHIMA, Japan
    Miyata Eye Hospital, MIYAKONOZYO, Japan
  • Takehiro Yamashita
    Kagoshima Univerrsity, KAGOSHIMA, Japan
  • Hiroto Terasaki
    Kagoshima Univerrsity, KAGOSHIMA, Japan
  • Kazunori Miyata
    Miyata Eye Hospital, MIYAKONOZYO, Japan
  • Yusuke Murakami
    Kyushu University , FUKUOKA, Japan
  • Yasuhiro Ikeda
    Kyushu University , FUKUOKA, Japan
  • Shozo Sonoda
    Kagoshima Univerrsity, KAGOSHIMA, Japan
  • Takeshi Morimoto
    Osaka University, OSAKA, Japan
  • Takao Endo
    Osaka University, OSAKA, Japan
  • junko kamo
    Kofu Kyoritsu Hospital, KOFU, Japan
  • Takashi Fujikado
    Osaka University, OSAKA, Japan
  • Taiji Sakamoto
    Kagoshima Univerrsity, KAGOSHIMA, Japan
  • Footnotes
    Commercial Relationships   Mayumi Sainohira, None; Takehiro Yamashita, None; Hiroto Terasaki, None; Kazunori Miyata, None; Yusuke Murakami, None; Yasuhiro Ikeda, None; Shozo Sonoda, None; Takeshi Morimoto, None; Takao Endo, None; junko kamo, None; Takashi Fujikado, None; Taiji Sakamoto, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science July 2018, Vol.59, 3410. doi:
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      Mayumi Sainohira, Takehiro Yamashita, Hiroto Terasaki, Kazunori Miyata, Yusuke Murakami, Yasuhiro Ikeda, Shozo Sonoda, Takeshi Morimoto, Takao Endo, junko kamo, Takashi Fujikado, Taiji Sakamoto; Anxiety, Depression and Vision- Related Quality of Life in Patients with Retinitis Pigmentosa.. Invest. Ophthalmol. Vis. Sci. 2018;59(9):3410.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : Retinitis Pigmentosa (RP) is an inherited, progressive retinal disease that can lead to severe visual loss. However, there is no effective treatment for RP. They can have a seriously psychological stress and the affected quality of life. This study was aimed to determine anxiety and depression state and Vision-
Related Quality of Life (VRQOL) in patients with RP.

Methods : A prospective, non-interventional study enrolled 110 patients (female 65, male 45) with RP and 57 healthy subjects (female 33, male 24). Anxiety and depression were assessed using the Hospital Anxiety and Depression Scale (HADS) , VRQOL with the National Eye Institute Visual Functioning Questionnaire-25 (VFQ-25). The Mann-Whitney test was used to evaluate differences between the RP patients and healthy subjects for the scores of HADS-A, HADS-D and the mean composite score of the VFQ-25.

Results : There were no significant differences in age (P=0.07) and sex (P=1.0) between the RP patients and healthy subjects. There were significant differences the scores of HADS-A (P=0.02), HADS-D (P<0.001) and the mean composite score of the VFQ-25 (P<0.001) between the RP patients and healthy subjects.

Conclusions : Patients with RP have not only the anxiety but also depression symptom in comparison to healthy Subjects. Furthermore, poor VRQOL may promote the anxiety and the depression. We should be careful about the states of affairs of the RP patients with ophthalmology views.

This is an abstract that was submitted for the 2018 ARVO Annual Meeting, held in Honolulu, Hawaii, April 29 - May 3, 2018.

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