July 2018
Volume 59, Issue 9
Open Access
ARVO Annual Meeting Abstract  |   July 2018
Evaluating the microbial profile of infectious keratitis and conjunctivitis at a public tertiary care hospital
Author Affiliations & Notes
  • Jennifer Lopez
    NYU School of Medicine, San Jose, California, United States
  • Edmund Tsui
    NYU School of Medicine, San Jose, California, United States
  • Leela V Raju
    NYU School of Medicine, San Jose, California, United States
  • Footnotes
    Commercial Relationships   Jennifer Lopez, None; Edmund Tsui, None; Leela Raju, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science July 2018, Vol.59, 3680. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      Jennifer Lopez, Edmund Tsui, Leela V Raju; Evaluating the microbial profile of infectious keratitis and conjunctivitis at a public tertiary care hospital. Invest. Ophthalmol. Vis. Sci. 2018;59(9):3680.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Purpose : To characterize corneal and conjunctival microbial profiles of patients from Bellevue Hospital, a large New York public hospital.

Methods : All eye cultures from 2009 to 2015 at Bellevue Hospital were retrospectively reviewed. All cultures, antibiotic sensitivities, and clinical courses were analyzed.

Results : Of the 451 eye cultures reviewed, 155 (34%) were positive. Of the positive cultures, 46 (30%) were corneal scrapings and 29 (19%) were conjunctival. Of the 46 positive corneal ulcer cultures, the most common isolates were P. aeruginosa (39%), S. marscescens (17%), and S. viridans (11%). Of P. aeruginosa cultures, 44% were resistant to cefuroxime while the rest were pansensitive. All S. marscescens cultures were resistant to cefazolin and cefuroxime. All S. viridans cultures were resistant to erythromycin. Among the 29 positive conjunctiva cultures, the most common isolates were coagulase negative staphylococci (34%), S. viridans group (17%), S. aureus MRSA (17%), and S. aureus MSSA (14%). Three of the MRSA cultures were also resistant to sulfamethoxazole/trimethoprim and two were resistant to erythromycin and tetracycline.

Conclusions : Corneal ulcer cultures most frequently grew bacteria, with P. aeruginosa being the most common organism. This is consistent with current literature showing that P. aeruginosa is a common isolate often due to contact lens wear. Given the resistance patterns of corneal ulcers, fluoroquinolones continue to be an effective choice of treatment. While most conjunctival cultures grew bacteria consistent with normal skin flora, many grew S. aureus with over half comprising of MRSA.

This is an abstract that was submitted for the 2018 ARVO Annual Meeting, held in Honolulu, Hawaii, April 29 - May 3, 2018.

×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×