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Adriana Grigorian; The Role of VEP in Determining Treatment Prognosis in Amblyopia. Invest. Ophthalmol. Vis. Sci. 2018;59(9):4119.
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© ARVO (1962-2015); The Authors (2016-present)
To analize the value of VEP in determining the amblyopia prognosis as well as its utility in determining the patch effect in the non-amblyopic eye
Chart review of all patients with amblyopia that underwent pattern reversal VEP testing. 19 patients were identified with ages between 5-18 years.To evaluate the patch effect, P100 latency <110ms was considered normal, 110-120ms borderline, and >120ms abnormal. To evaluate the prognosis of visual improvement in the amblyopic eye, P100 latency< 110ms was considered good, 110-130ms was considered fair, and >130ms poor.
Prognosis for final visual acuity was:Good in 4 patients - P100 <110ms-average VA 20/55 in the amblyopic eye at time of testingFair in 5 patients - P100 110-130ms- average VA 20/50Poor in 10 patients - P100 >130ms-average VA 20/81Patch effect was observed in 2 patients and was borderline in 3 of the 19 patients. 4 of these 5 patients had a strabismic component based on diagnosis.
VEP may provide additional clinical utility in the management of amblyopia by giving prognostic information and helping the clinician tailor the treatment in order to avoid both under and over-treatment. Future research can further improve understanding of the utility of VEP in determining the prognosis of amblyopia as well as in early detection of the patch effect.
This is an abstract that was submitted for the 2018 ARVO Annual Meeting, held in Honolulu, Hawaii, April 29 - May 3, 2018.
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