Abstract
Purpose :
To describe and correlate the abnormal findings between Fundus Autofluorescence (FAF) and Swept-Source Optical Coherence Tomography (SS-OCT) in patients with macula-off rhegmatogenous retinal detachment (RRD), before and after surgery
Methods :
A descriptive, longitudinal and prospective study of 36 eyes with macula-off RRD, between august 2016 and september 2017. The images were taken before surgery and at day 1, 1 week, 1 month and 3 months after surgery in all patients. To evaluate and localize the abnormal findings, we used SS-OCT integrated with a fundus camera (DRI OCT Triton, Topcon). FAF images were obtained using excitation filters in the green spectrum (about 550nm)
Results :
The FAF results revealed that almost all types of autofluorescence abnormalities were correlated with welldefined morphologic alterations in SS-OCT. 100% of the eyes demostrated hyperautofluorescence, and were classificated in different patterns : diffuse (100%), linear (97%; five subtypes), foveal (33%), and a pattern associated to proliferative vitreoretinopathy (PVR). 33% of eyes presented hypoautofluorescence
Conclusions :
The different patterns of hyperautoflueorescence found in the FAF correspond to changes in SS-OTC: diffuse (increase in the length of the external segments (ES) of photoreceptors (PR) and a slow turn over), liner with corrugations (posterior ondulations of the neurosensory retina that allow the overlapping of the enlarged ES of PR),linear foldings (folding of the ellipsoid zone and external limiting membrane, always associates adjacent hypoautofluorescent line, on each side of the fold), linear edges (the accumulation and fold of retinal external bands in the edge of reattachment), linear paravascular impressions (show how much of retinal shift or displacement comes out after surgery), foveal (with subfoveal fluid and ES increased in size and reflectivity, and a very thin neurosensory retina, that results in hyperautofluorescence and an increment in the transmission). The diffuse patterns of hypoautofluorescence were associated with areas of severe loss of the external structures of the retina, particularly internal and external segments of the photoreceptors, and the local zones of hypoautofluorescence were associated with subrretinal blood or delimited defects in the retinal pigment epithelium
This is an abstract that was submitted for the 2018 ARVO Annual Meeting, held in Honolulu, Hawaii, April 29 - May 3, 2018.