July 2018
Volume 59, Issue 9
Free
ARVO Annual Meeting Abstract  |   July 2018
Observation of Vitreous Features Using Enhanced Vitreous Imaging Optical Coherence Tomography in Highly Myopic Retinoschisis
Author Affiliations & Notes
  • Minlu Song
    Ophthalmology, Shanghai General Hospital , Shanghai Jiao Tong University School of Medicine, Shanghai, China
  • Mengxi Shen
    Ophthalmology, Shanghai General Hospital , Shanghai Jiao Tong University School of Medicine, Shanghai, China
  • Yanping Zhou
    Ophthalmology, Zhongshan Hospital, Fudan University, Shanghai, China
  • Kairong Zheng
    Ophthalmology, Shanghai General Hospital , Shanghai Jiao Tong University School of Medicine, Shanghai, China
  • Yuanqi Zhai
    Ophthalmology, Shanghai General Hospital , Shanghai Jiao Tong University School of Medicine, Shanghai, China
    Shanghai Key Laboratory of Fundus Diseases, Shanghai, China
  • Meichun Xiao
    Ophthalmology, Shanghai General Hospital , Shanghai Jiao Tong University School of Medicine, Shanghai, China
  • Xiaohan Wang
    Ophthalmology, Shanghai General Hospital , Shanghai Jiao Tong University School of Medicine, Shanghai, China
  • Fenghua Wang
    Ophthalmology, Shanghai General Hospital , Shanghai Jiao Tong University School of Medicine, Shanghai, China
    Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai, China
  • Xiaodong Sun
    Ophthalmology, Shanghai General Hospital , Shanghai Jiao Tong University School of Medicine, Shanghai, China
    Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai, China
  • Footnotes
    Commercial Relationships   Minlu Song, None; Mengxi Shen, None; Yanping Zhou, None; Kairong Zheng, None; Yuanqi Zhai, None; Meichun Xiao, None; Xiaohan Wang, None; Fenghua Wang, None; Xiaodong Sun, None
  • Footnotes
    Support  NSFC Grant 81470640
Investigative Ophthalmology & Visual Science July 2018, Vol.59, 4737. doi:
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      Minlu Song, Mengxi Shen, Yanping Zhou, Kairong Zheng, Yuanqi Zhai, Meichun Xiao, Xiaohan Wang, Fenghua Wang, Xiaodong Sun; Observation of Vitreous Features Using Enhanced Vitreous Imaging Optical Coherence Tomography in Highly Myopic Retinoschisis. Invest. Ophthalmol. Vis. Sci. 2018;59(9):4737.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : High myopia is associated with an increased risk of developing various ocular pathology and early vitreous changes. We performed enhanced vitreous imaging optical coherence tomography (EVI-OCT) to observe features of the posterior vitreous and vitreoretinal interface in highly myopic eyes with retinoschisis.

Methods : Comprehensive ophthalmologic examination and EVI-OCT were performed in 77 eyes of 63 patients with highly myopic retinoschisis. Two different modes of spectral domain optical coherence tomography (SD-OCT) were employed to estimate retinoschisis and the posterior vitreous features in OCT images, respectively. The types and distribution of vitreoretinal interface abnormalities were also analyzed.

Results : Complete posterior vitreous detachment (PVD) was identified in 55 eyes (71.4%) with a Weiss ring. Residual cortex was found in 39 eyes (70.9%) with complete PVD. Vitreoretinal interface changes, including vitreoretinal adhesion (VA) and epiretinal membrane (ERM), most frequently appeared in the macular area (47.3%), followed by the inferior arched vessels region (34.5%). In partial PVD eyes, vitreoretinal traction (VT), VA and ERM tended to be observed in the inferior and superior arched vessels regions (54.5% and 40.9%, respectively). Among all types of vitreoretinal abnormalities, ERM comprised the largest proportion (46.8%) despite the status of PVD. The presence of inner layers of retinoschisis connoted a relatively high possibility of vitreoretinal interface abnormalities occurring.

Conclusions : EVI-OCT reveals a high prevalence of vitreoretinal interface abnormalities in highly myopic eyes with retinoschisis. Vitreous cortex tends to remain on the macular area in eyes with complete PVD. Further understanding and longitudinal investigation of the vitreoretinal interface factors would lead to better guidance for the surgical treatment of highly myopic retinoschisis.

This is an abstract that was submitted for the 2018 ARVO Annual Meeting, held in Honolulu, Hawaii, April 29 - May 3, 2018.

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