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Bingqian Liu, Haocheng Ao, Limei Sun, Lin Lu; Association between subfoveal choroidal thickness and Progression of Macular Schisis in highly myopic eyes. Invest. Ophthalmol. Vis. Sci. 2018;59(9):4740.
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© ARVO (1962-2015); The Authors (2016-present)
To investigate the association between progression of macular schisis and subfoveal choroidal thickness (SFCT) in highly myopic eyes
Ninety-nine consecutive highly myopic eyes (axial length ≥ 26.0mm) from 83 patients showing myopic macular schisis (MMS) on OCT and followed for at least 12 months were included. The eyes were divided into three groups according to OCT changes between the last visit and baseline. Progressive group was defined as deteriorated anatomic changes (increase of macular retinal thickness, development of retinoschisis toward normal area, development of foveal detachment, or full thickness macular hole). Spontaneously improved group was defined as reversed progression of progressive group. Stable group was defined as the anatomic features that did not show anatomic deterioration or spontaneous improvement. SFCT, axial length, best corrected visual acuity (BCVA) was measured on OCT and compared between the three groups.
In our cohort, 53 eyes were stable, 34 eyes were progressive, 12 eyes showed spontaneous improvement. There was no statistical difference between the three groups in age, axial length, refractive error, or baseline BCVA. At last visit, the mean best corrected visual acuity changed -9.8, -0.9, and +3.4 ETDRS letters in progressive group (p<0.001), stable group (p=0.304), and spontaneously improved group (p<0.01), respectively. SFCT was significantly thicker in spontaneously improved group (110.3±17.5 μm) than the other two groups (p<0.01). There was no difference in SFCT of stable group (69.6 ± 41.6 μm) and progressive group (75.6±34.1 μm) (p>0.05).
Thicker SFCT was associated with spontaneous improvement of MMS, which might indicate the retinochoroidal degeneration was less severe in this group of eyes.
This is an abstract that was submitted for the 2018 ARVO Annual Meeting, held in Honolulu, Hawaii, April 29 - May 3, 2018.
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