July 2018
Volume 59, Issue 9
Open Access
ARVO Annual Meeting Abstract  |   July 2018

Predictive factors of selective retina therapy for diabetic macular edema
Author Affiliations & Notes
  • Kumiko Hirayama
    opthalmology, Osaka City University, Osaka, Japan
  • Manabu Yamamoto
    opthalmology, Osaka City University, Osaka, Japan
  • Takeya Kohno
    opthalmology, Osaka City University, Osaka, Japan
  • Dirk Theissen-Kunde
    Medical Laser Center Luebeck, Lubeck, Germany
  • Yoko Miura
    Medical Laser Center Luebeck, Lubeck, Germany
    Institute of Biomedical Optics, University of Luebeck, Lubeck, Germany
  • Ralf Brinkmann
    Medical Laser Center Luebeck, Lubeck, Germany
  • Kunihiko Shiraki
    opthalmology, Osaka City University, Osaka, Japan
  • Footnotes
    Commercial Relationships   Kumiko Hirayama, None; Manabu Yamamoto, None; Takeya Kohno, None; Dirk Theissen-Kunde, None; Yoko Miura, None; Ralf Brinkmann, None; Kunihiko Shiraki, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science July 2018, Vol.59, 4831. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      Kumiko Hirayama, Manabu Yamamoto, Takeya Kohno, Dirk Theissen-Kunde, Yoko Miura, Ralf Brinkmann, Kunihiko Shiraki;
      Predictive factors of selective retina therapy for diabetic macular edema. Invest. Ophthalmol. Vis. Sci. 2018;59(9):4831.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Purpose :
To investigate the predictive factors of Selective Retina Therapy (SRT) for diabetic macular edema (DME).

Methods :
This retrospective study included 19 eyes of 16 patients (9 males and 7 females), who were treated with SRT for DME at the department of Ophthalmology of Osaka City University Hospital, and observed at least 6 months after treatment. Mean age was 64 years old (range 46-75). Eleven of the 19 eyes (58%) had a treatment history other than SRT. SRT laser (527 nm, 1.7 µs, 100 Hz; Medical Laser Center Lübeck, Germany) was used for treatment. The changes of logMAR best corrected visual acuity (BCVA) and central macular thickness (CMT) in optical coherence tomography (OCT) were examined at baseline, 3-month follow-up, and 6-month follow-up. We defined the decrease of >15% of CMT compared to pretreatment as ‘improvement’. Association between the clinical characteristics at baseline and the incidence of “improvemnet” was analyzed.

Results :
The mean logMAR BCVA was 0.27±0.32, 0.21±0.23 and 0.27±0.31 at baseline, 3 months, and 6 months, respectively (P=0.09 at 3 months, 0.94 at 6 months; as compared with baseline). The mean CMT was 486±145 μm, 449±180 μm, 413±181 μm at baseline, 3 months, and 6 months, respectively (P=0.16 at 3 months, <0.05 at 6 months; as compared with baseline). The history of macular photocoagulation was significantly negatively associated with the incidence of “improvement” (P=0.02).

Conclusions :
The CMT was significantly decreased at 6 months after SRT in DME. The history of macular photocoagulation may adversely affect the effect of SRT.

This is an abstract that was submitted for the 2018 ARVO Annual Meeting, held in Honolulu, Hawaii, April 29 - May 3, 2018.

×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×