July 2018
Volume 59, Issue 9
Open Access
ARVO Annual Meeting Abstract  |   July 2018
Direct photocoagulation guided with merged retinal images for the treatment of focal diabetic macular edema.
Author Affiliations & Notes
  • Yoshihiro Takamura
    Ophthalmology, University of Fukui, Yoshida, FUkui, Japan
  • takehiro matsumura
    Ophthalmology, University of Fukui, Yoshida, FUkui, Japan
  • Shogo Arimura
    Ophthalmology, University of Fukui, Yoshida, FUkui, Japan
  • makoto gozawa
    Ophthalmology, University of Fukui, Yoshida, FUkui, Japan
  • masakazu morioka
    Ophthalmology, University of Fukui, Yoshida, FUkui, Japan
  • Yutaka Yamada
    Ophthalmology, University of Fukui, Yoshida, FUkui, Japan
  • Masaru Inatani
    Ophthalmology, University of Fukui, Yoshida, FUkui, Japan
  • Footnotes
    Commercial Relationships   Yoshihiro Takamura, None; takehiro matsumura, None; Shogo Arimura, None; makoto gozawa, None; masakazu morioka, None; Yutaka Yamada, None; Masaru Inatani, None
  • Footnotes
    Support  Publication of this article was supported in part by grants-in aid for scientific research (Nos. 24592620) from the Japan Society for the Promotion of Science, Tokyo, Japan.
Investigative Ophthalmology & Visual Science July 2018, Vol.59, 4853. doi:
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    • Get Citation

      Yoshihiro Takamura, takehiro matsumura, Shogo Arimura, makoto gozawa, masakazu morioka, Yutaka Yamada, Masaru Inatani; Direct photocoagulation guided with merged retinal images for the treatment of focal diabetic macular edema.. Invest. Ophthalmol. Vis. Sci. 2018;59(9):4853.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To introduce a novel laser photocoagulation (PC) protocol, named the Merged Images of fundus photograph, optical coherence tomography (OCT)-map, and fluorescein angiography (FA) Guided PC (MIG-PC). We compared the anatomic and functional results using the MIG-PC and FA-Guided PC (FG-PC) for the treatment of the focal diabetic macular edema (DME).

Methods : We examined the outcomes of treatment in 27 consecutive eyes treated with MIG-PC compared to 28 matched eyes treated with FG-PC. We identified the microaneurysms (MAs) located in the focal edema areas, and ablated them with focal PC. Best-corrected visual acuity (BCVA) and retinal thickness (RT) measured by OCT were compared between the groups at baseline, 2, 4, 8, 12 and 24 weeks after treatment.

Results : The foveal and perifoveal RT was reduced after treatment in both groups, and perifoveal RT in the MIG-PC group was significantly lower than that in the FG-PC group at 4 weeks and thereafter. BCVA in the MIG-PC group was significantly better than that of FG-PC group at 12 and 24 weeks. The number of laser spots (p = 0.0001), additional laser (p = 0.0121), and intravitreal injection of ranibizumab (p = 0.0012) in the MIG-PC group was significantly smaller than those in the FG-PC group (Mann–Whitney test).

Conclusions : The MIG-PC was contributed to the improvement of BCVA and the reduction of retinal thickness, the number of laser shots required, and the retreatment rates. Based on our data, the MIG-PC should be recommended in the treatment of focal DME.

This is an abstract that was submitted for the 2018 ARVO Annual Meeting, held in Honolulu, Hawaii, April 29 - May 3, 2018.

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