Purchase this article with an account.
Yoshihiro Takamura, takehiro matsumura, Shogo Arimura, makoto gozawa, masakazu morioka, Yutaka Yamada, Masaru Inatani; Direct photocoagulation guided with merged retinal images for the treatment of focal diabetic macular edema.. Invest. Ophthalmol. Vis. Sci. 2018;59(9):4853.
Download citation file:
© ARVO (1962-2015); The Authors (2016-present)
To introduce a novel laser photocoagulation (PC) protocol, named the Merged Images of fundus photograph, optical coherence tomography (OCT)-map, and fluorescein angiography (FA) Guided PC (MIG-PC). We compared the anatomic and functional results using the MIG-PC and FA-Guided PC (FG-PC) for the treatment of the focal diabetic macular edema (DME).
We examined the outcomes of treatment in 27 consecutive eyes treated with MIG-PC compared to 28 matched eyes treated with FG-PC. We identified the microaneurysms (MAs) located in the focal edema areas, and ablated them with focal PC. Best-corrected visual acuity (BCVA) and retinal thickness (RT) measured by OCT were compared between the groups at baseline, 2, 4, 8, 12 and 24 weeks after treatment.
The foveal and perifoveal RT was reduced after treatment in both groups, and perifoveal RT in the MIG-PC group was significantly lower than that in the FG-PC group at 4 weeks and thereafter. BCVA in the MIG-PC group was significantly better than that of FG-PC group at 12 and 24 weeks. The number of laser spots (p = 0.0001), additional laser (p = 0.0121), and intravitreal injection of ranibizumab (p = 0.0012) in the MIG-PC group was significantly smaller than those in the FG-PC group (Mann–Whitney test).
The MIG-PC was contributed to the improvement of BCVA and the reduction of retinal thickness, the number of laser shots required, and the retreatment rates. Based on our data, the MIG-PC should be recommended in the treatment of focal DME.
This is an abstract that was submitted for the 2018 ARVO Annual Meeting, held in Honolulu, Hawaii, April 29 - May 3, 2018.
This PDF is available to Subscribers Only