July 2018
Volume 59, Issue 9
Open Access
ARVO Annual Meeting Abstract  |   July 2018
Ocular surface involvement on GVHD patients
Author Affiliations & Notes
  • Lazreg Sihem
    Blida, Cabinet Dr Lazreg, Blida, Algeria
  • renault didier
  • Footnotes
    Commercial Relationships   Lazreg Sihem, None; renault didier, None
  • Footnotes
    Support  none
Investigative Ophthalmology & Visual Science July 2018, Vol.59, 4877. doi:
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      Lazreg Sihem, renault didier; Ocular surface involvement on GVHD patients
      . Invest. Ophthalmol. Vis. Sci. 2018;59(9):4877.

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      © ARVO (1962-2015); The Authors (2016-present)

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Purpose : To identify the different complications of GVHD on ocular surface;

Methods : ocular surface examination on patients with GVHD , referred by the center of bone marrow graft of Algiers, all benefited from OSDI questionnary, slit lamp examination, fluorescein coloration and Schirmer test,

Results : 127 patients were assessed, the mean age value was 39,3 years+/_ 7,4; all patients presented different levels of severity of dry eye at slit lamp examination, 5% of them had a very low visual acuity; Mean OSDI score was 76,4+/_10,2 corneal staining was present on 92% of cases (oxford : 6,5+/_ 2,5) and Schirmer value 10+/_5,4 ),

Conclusions : Dry eye is the most common ocular complication on GVHD patients, in most of cases it is a severe dry eye with corneal involvement and visual impairment, an early diagnosis and treatment of ocular manifestations of GVHD is essential to prevent severe complications.

This is an abstract that was submitted for the 2018 ARVO Annual Meeting, held in Honolulu, Hawaii, April 29 - May 3, 2018.


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