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Yoshiki Tanaka, Hiroyuki Sato, Rie Horai, Sho Yokoyama, Mari Mitamura, Kazuo Ichikawa, Shoko Tanabe; Visual field using color information by healthy subject. Invest. Ophthalmol. Vis. Sci. 2018;59(9):5109.
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© ARVO (1962-2015); The Authors (2016-present)
In recent years, the development of ophthalmic examination equipment enabled the early detection of glaucoma. In particular, the optical coherence tomography (OCT) can be detects the structural changes on the retina before the abnormality is found by the automatic static perimeter. We considered that the sensitivity of the current automatic static perimeter should be more sensitive by using color information. The Short Wavelength Automated Perimetry (SWAP) is well known as the detection method of early visual field loss. However, the background light intensity of SWAP is very high, to undergo this examination is painful. Therefore, we developed new perimetric method by using color information.
Seventeen normal subject and 17 eyes were enrolled under this study. None of the subjects had any ocular disease or color anomaly except for refractive error. The mean age of the participants was 30.3 ± 6.1 years (age range, 22-49 years). The mean spherical equivalent was -3.80 ± 2.93, while the best corrected visual acuity was 20/13 or more. Red (R: red-green axis color) and Blue-Purple (BP: blue-yellow axis color) were used as stimulus colors. The background color was achromatic (D65) and was set to the same luminance with the stimulus colors. CG245W (EIZO corporation) was adopted for the measuring the visual field. The measurement points of visual field were 16 points on macular (the measurement range of visual field was ±3°). The thresholds of each visual field point were decided by the minimum visible size (LogMAR) of stimulus.
The average threshold value (LogMAR value) that were nearest 4 points stimulus from the center of visual field were R: 0.914±0.096 and BP: 1.123±0.154. Moreover, the average threshold value (LogMAR value) that were farthest 4 points stimulus from the center of visual field were R: 1.146 ± 0.106 and BP : 1.227 ± 0.124. There were significant difference in threshold values between R and BP for each distance (the p value were p < 0.0001 and p < 0.0001 respectively by Wilcoxon matched pairs test).
This result means that the S-cone ability is not good in the vicinity of fovea because of the S-cone is not exist on fovea centralis as well as the number of S-cone is poor compared with L and M-cone. Therefore we consider that our perimetric method using color information is useful to evaluate the cone function. In the future, we will conduct the clinical examinations for eye disease patients.
This is an abstract that was submitted for the 2018 ARVO Annual Meeting, held in Honolulu, Hawaii, April 29 - May 3, 2018.
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