July 2018
Volume 59, Issue 9
Open Access
ARVO Annual Meeting Abstract  |   July 2018
Visual Outcomes after Side Ports Lensectomy and Intraocular Lens Trans-Scleral Sulcus Suture Fixation in Pediatric Marfan Syndrome.
Author Affiliations & Notes
  • Minjae Kim
    Ophthalmology, University of Tokyo, Shinden, Adachi-ku, Japan
  • Takuya Nakajima
    Ophthalmology, University of Tokyo, Shinden, Adachi-ku, Japan
  • Miyuki Nagahara
    Ophthalmology, University of Tokyo, Shinden, Adachi-ku, Japan
  • Footnotes
    Commercial Relationships   Minjae Kim, None; Takuya Nakajima, None; Miyuki Nagahara, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science July 2018, Vol.59, 5194. doi:
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      Minjae Kim, Takuya Nakajima, Miyuki Nagahara; Visual Outcomes after Side Ports Lensectomy and Intraocular Lens Trans-Scleral Sulcus Suture Fixation in Pediatric Marfan Syndrome.. Invest. Ophthalmol. Vis. Sci. 2018;59(9):5194.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To evaluate clinical outcomes with combined side ports lensectomy and small incision intraocular lens (IOL) implantation with trans-scleral sulcus suture fixation in pediatric Marfan syndrome.

Methods : A retrospective analysis of medical records of 17 eyes (Male 11 eyes, Female 6 eyes) with sub-luxated lens induced monocular diplopia in pediatric Marfan syndrome who underwent side ports lensectomy with 25G vitrector and small incision (2.75mm) IOL implantation with trans-scleral sulcus suture fixation from Dec 2004 to July 2016 in the University of Tokyo Hospital and the Tokai University Hachioji Hospital was reviewed.
Preoperative and postoperative parameters were best corrected visual acuity (BCVA), corneal curvature, refractive cylinder power, corneal cells loss and intraocular pressure (IOP). Postoperative complications were evaluated with wound leakage, hemorrhage, iris capture, cystoid macula edema, IOL dislocation, retinal detachment and endophthalmitis. Wilcoxon’s signed-rank test was used to analyze each parameter.

Results : The mean age was 7.6±4.6 (mean±SD) ranged from 4 to 18 years old. A 6.0mm optic diameter of IOL was put in 6 eyes, a 6.5mm optic diameter was put in 7 eyes and a 7mm was put in 4 eyes. At 1-year follow-up, the mean BCVA (logMAR) was increased from 0.87 (median) to -0.03 (p<0.01). The mean refractive cylinder power was 1.53±1.01D (mean±SD), corneal astigmatism, cornel cells loss and IOP were no significant difference before and after surgery. Repeated iris capture was observed in eyes with or without peripheral iridectomy, however, it was decreased after 6 months. There are no severe complications after surgery.

Conclusions : Monocular diplopia was disappeared and visual acuity was excellent improved after surgery. Long-term follow-up is needed to observe complications, however, this surgical procedure should be considered for low vision treatment in Pediatric Marfan Syndrome.

This is an abstract that was submitted for the 2018 ARVO Annual Meeting, held in Honolulu, Hawaii, April 29 - May 3, 2018.

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