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Yufei Teng, Wu Liu; Evaluation of the choriocapillary vessel density in unilateral idiopathic macular hole after vitrectomy. Invest. Ophthalmol. Vis. Sci. 2018;59(9):5275.
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© ARVO (1962-2015); The Authors (2016-present)
Our pervious study had identified the choriocapillary circulation in eyes with unilateral idiopathic macular hole (IMH) were significantly increased one month after vitrectomy. In this study, we determined the change of choriocapillary vessel density in longer follow up time after microincision vitrectomy.
16 patients (15 females, 1 male，mean age 62 years) with idiopathic macular hole (IMH) who performed microvitrectomy surgery were recruited, All patients had gone through 23G PPV+ILM peeling+ gas injection(C3F8). The follow up period were from 3 months to 2 years. Choriocapillary vessel density was obtained by using Angio Optical Coherence Tomography (OCTA). The vessel density was measured at the area 1 mm diameter from the fovea.
The choriocapillary vessel density in IMH eyes and unaffected fellow eyes exhibited to be the same trend in the longer follow up time after operation (p=0.312, Wilcoxon matched-pairs signed rank test). The median of choriocapillaris vessel density was 0.615 mm2 in the IMH group, and 0.605 mm2 in the unaffected fellow eyes group. This result was differing from our previous finding that in short-term observation (1 month after operation), choriocapillary vessel density of IMH eyes was still lower than that of unaffected fellow eyes. Indicating that in the long run, the choriocapillary vessel flow can return to a normal level. Correlation analysis was performed between the ratio of choriocapillary vessel density of IMH/ unaffected fellow eyes and the month after operation, as well as the BCVA, no significant correlation was found between different parameters.
Our pervious study revealed the hypoperfusion of choroidal circulations in IMH could be restored following the repair of macular hole. In long-term observation, the choriocapillary perfusion can return to the normal level, which supporting our hypothesis that the defect of macular retina may temporarily reduce the focal needing of blood-supply and diminish the choroidal circulation.
This is an abstract that was submitted for the 2018 ARVO Annual Meeting, held in Honolulu, Hawaii, April 29 - May 3, 2018.
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