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Mai Badr, Marisse Masis, Behzad Amoozgar, Anwell Nguyen, Shan C Lin; Central Corneal Thickness Variances Among Different Asian Ethnicities In Glaucoma And Non-glaucoma Patients. Invest. Ophthalmol. Vis. Sci. 2018;59(9):5892.
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© ARVO (1962-2015); The Authors (2016-present)
To compare the central corneal thickness (CCT) between different ethnicities and particularly Asian subethnic groups that may contribute to the different glaucoma diagnosis using the Lenstar Optical Biometer.
A retrospective study of 6 years including 1,512 eyes of 930 patients of the Beckman vision center, University of California, San Francisco (UCSF) from July 2011 to June 2017 had their biometric parameters, including CCT and AL, measured with the Lenstar Optical Biometer (Ohio, USA). Patients were categorized according to the self-reported race into African Americans, Caucasians, Hispanics, Pacific Islanders, and Asians. Asians were further subcategorized into Chinese, Vietnamese, Koreans, Filipinos and Japanese.
Out of 1356 patients who had their CCT measured by Lenstar in the period from 2011 to 2017, 1512 eyes of 930 patients were included in the study. The study population included 462 Caucasians (49.7%), 60 African Americans (6.45%), 93 Hispanics (10%), 32 Pacific Islanders (3.44%) and 283 Asians (30.43%). Asians were further subcategorized into 130 Chinese (45.94%), 52 Filipinos (18.37%), 37 Vietnamese (13.07%), 34 Koreans (12.01%) and 30 Japanese (10.6%). The thinnest CCT was found in the African American population with a mean of 518.62 ± 40.3 followed by Asians with a mean of 539.29 ± 34.1 then Hispanics with a mean of 540.30 ± 34.7 while the thickest CCT was found among Caucasians with a mean of 547.44 ± 34.1. Among the Asian study sample, the Chinese had the thinnest CCT with a mean of 537.66 ± 32.5. CCT was adjusted for gender, glaucoma diagnosis, axial length (AL), diabetes status and prostaglandin analogues use for a duration of more than 12 months.
Lenstar is a widely used technology, which can also provide corneal thickness information. Our study confirms in a big population that subjects within African American population have thinner corneas followed by the Asian subgroup. Additionally, among the Asian population group, the thinnest CCT was found among the Chinese.
This is an abstract that was submitted for the 2018 ARVO Annual Meeting, held in Honolulu, Hawaii, April 29 - May 3, 2018.
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