July 2018
Volume 59, Issue 9
Open Access
ARVO Annual Meeting Abstract  |   July 2018

Biometric factors associated with acute primary angle closure: A comparison of the affected and eyes with a similar short axial length
Author Affiliations & Notes
  • Yoshiaki Kiuchi
    Ophthalmology, Tsukazaki Hospital, Himeji, Japan
  • Yukiko Shimizu
    Ophthalmology, Tsukazaki Hospital, Himeji, Japan
  • Shunsuke Nakakura
    Ophthalmology, Tsukazaki Hospital, Himeji, Japan
  • Asuka Noguchi
    Ophthalmology, Tsukazaki Hospital, Himeji, Japan
  • Hitoshi Tabuchi
    Ophthalmology, Tsukazaki Hospital, Himeji, Japan
  • Footnotes
    Commercial Relationships   Yoshiaki Kiuchi, Alcon (F), Ellex (C), Novartis (F), Santen (F); Yukiko Shimizu, None; Shunsuke Nakakura, None; Asuka Noguchi, None; Hitoshi Tabuchi, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science July 2018, Vol.59, 5898. doi:
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    • Get Citation

      Yoshiaki Kiuchi, Yukiko Shimizu, Shunsuke Nakakura, Asuka Noguchi, Hitoshi Tabuchi;
      Biometric factors associated with acute primary angle closure: A comparison of the affected and eyes with a similar short axial length. Invest. Ophthalmol. Vis. Sci. 2018;59(9):5898.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : A short axial length is a major risk for acute angle closure. However, not all eyes with a short axial length experience acute attack. The purpose of this study was to clarify the difference in the biometric factors of the anterior segment in acute primary angle closure eyes and eyes with a similar short axial length.

Methods :
This retrospective study was carried out at the Department of Ophthalmology of Tsukazaki Hospital in Himeji, Japan. Anterior segment optical coherence tomography (AS-OCT) CASIA (Tomey Corporation, Nagoya, Japan) was used to examine 27 eyes of 27 patients with acute angle closure (A group), and 49 axial length- and age-adjusted eyes of 49 subjects with a short axial length (S group). After measuring the axial length, refractive error, corneal curvature, central corneal thickness, anterior chamber depth, angle opening distance 500 (AOD500), lens vault, anterior chamber width, and the perpendicular distance between the horizontal line joining the two scleral spurs and the back side of central cornea (anterior chamber height), multivariate regression analyses were performed to determine the factors predicting acute angle closure.

Results : The axial length (average: A group vs. S group: 22.80 vs. 22.39 mm) and refractive error (1.12 vs. 1.05 D) showed no significant differences. The corneal curvature (7.61 vs. 7.41 mm), central corneal thickness (579 vs. 521 µm), and lens vault (1.12 vs. 0.56 mm) of the A group were larger than in the S group. The anterior chamber depth (1.53 vs. 2.53 mm), AOD500 (0.09 vs. 0.37 mm), anterior chamber width (11.00 vs. 11.20 mm), and anterior chamber height (2.64 vs. 3.08 mm) of the A group were smaller than in the S group (p<0.05). The anterior chamber depth and AOD500 were selected as predictive factors for acute angle glaucoma (p<0.01, R2 = 1.0).

Conclusions : Acute angle closure eyes have a crowed anterior segment compared to eyes with a similar short axial length without acute attack. A shallow anterior chamber and small AOD500 were found to be associated with acute angle closure in short-axial-length eyes.

This is an abstract that was submitted for the 2018 ARVO Annual Meeting, held in Honolulu, Hawaii, April 29 - May 3, 2018.

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