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Joao Duvilio B Andreolli, Niro Kasahara, Ralph Cohen; BIOMICROSCOPIC FINDINGS IN PSEUDOEXFOLIATION SYNDROME AT SANTA CASA DE SÃO PAULO HOSPITAL. Invest. Ophthalmol. Vis. Sci. 2018;59(9):5903. doi: https://doi.org/.
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Although it is a frequent known cause of secondary glaucoma in the world, pseudo-exfoliation is an uncommon disease in Brazil. According to the literature, there are no studies investigating the preferential occurrence of PEX signs by quadrants. The purpose of this research is to describe the biomicroscopic findings of the pseudo-exfoliation syndrome in a cohort of brasilian patients and the secondarily endpoint was to investigate the preferencial occurrence of the findings per quadrant.
The study was an observational cross sectional analysis of 17 eyes from 10 patients with PEX evaluated before and after pharmacological mydriasis. Biomicroscopy and gonioscopy were performed and the findings were stratified according to quadrants.
The most frequent biomicroscopic findings in the eyes of PEX patients were peripheral zone (100%), intermediate zone (100%), Sampaolesi signal (94.11%), central disk (70.58%) and Iris deposits (47.05%). There were no differences of the PEX signs among quadrants.
The most frequent biomicroscopic findings of the PEX syndrome were deposition of pseudo-exfoliative material on the peripheral zone, the characteristic pigmentation of the anterior chamber angle (Sampaolesi's sign) and deposits of pseudo-exfoliative material on the pupillary border. There were no differences of findings beetween quadrants. The characteristic pigmentation of the anterior chamber angle, described by Sampaolesi, may be an early indicator of bilateral occurrence of the syndrome in eyes that do not yet present biomicroscopic findings on the lens.
This is an abstract that was submitted for the 2018 ARVO Annual Meeting, held in Honolulu, Hawaii, April 29 - May 3, 2018.
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