July 2018
Volume 59, Issue 9
Open Access
ARVO Annual Meeting Abstract  |   July 2018

Using a Novel Anterior Segment Optical Coherence Tomography (AS-OCT) Method to Assess Iridocorneal Angle
Author Affiliations & Notes
  • Mariana Nunez
    Ophthalmology, Byers Eye Institute at Stanford, Palo Alto, California, United States
  • Michelle Y. Chen
    Ophthalmology, Allergan, Irvine, California, United States
  • Susan S Lee
    Ophthalmology, Allergan, Irvine, California, United States
  • Chyong Nien
    Ophthalmology, Allergan, Irvine, California, United States
  • Felipe Medeiros
    Ophthalmology, Duke University, Durham, North Carolina, United States
  • Jeffrey L Goldberg
    Ophthalmology, Byers Eye Institute at Stanford, Palo Alto, California, United States
  • Footnotes
    Commercial Relationships   Mariana Nunez, None; Michelle Chen, Allergan (E); Susan Lee, Allergan (E); Chyong Nien, Allergan (E); Felipe Medeiros, Allergan (C); Jeffrey Goldberg, Allergan (C)
  • Footnotes
    Support  Grant support from Allergan
Investigative Ophthalmology & Visual Science July 2018, Vol.59, 5905. doi:
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    • Get Citation

      Mariana Nunez, Michelle Y. Chen, Susan S Lee, Chyong Nien, Felipe Medeiros, Jeffrey L Goldberg;
      Using a Novel Anterior Segment Optical Coherence Tomography (AS-OCT) Method to Assess Iridocorneal Angle. Invest. Ophthalmol. Vis. Sci. 2018;59(9):5905.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To assess iridocorneal angle by AS-OCT using a novel methodology and to compare assessment with clinical gonioscopy

Methods : Observational case series of patients with glaucoma or ocular hypertension. Iridocorneal angle images and measurements were made using images obtained from Heidelberg AS-OCT. The Schwalbe’s line was identified and a circle was drawn between the Schwalbe’s line and the iris. Diameter of the circle was used to approximate the iridocorneal angle width. Clinical gonioscopy images were also taken from the same location of the AS-OCT images and angles were graded based on Shaffer grading system and compared to the corresponding AS-OCT images for each eye.

Results : Thirty eyes were analyzed in this study. The average angle widths measured by AS-OCT were 166±42µm for Shaffer Grade 1, 349±49µm for Shaffer Grade 2, 447±106µm for Shaffer Grade 3, 563±128µm for Shaffer Grade 4. A positive correlation was found between angle width and clinical Shaffer grade (Pearson: 0.8, p<0.001).

Conclusions : In this study, angle width was measured by AS-OCT. A strong agreement was observed between measurements made from clinical gonioscopy and AS-OCT. AS-OCT also provides additional information that can be used in conjunctional with gonioscopy for iridocorneal angle assessments. Further studies with larger sample size will be needed to determine the validity and utility of implementing this method into clinical practice.

This is an abstract that was submitted for the 2018 ARVO Annual Meeting, held in Honolulu, Hawaii, April 29 - May 3, 2018.

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