Abstract
Purpose :
The axial length to corneal radius of curvature ratio (AL/CRC) value is associated with the development of myopia and may be a more useful marker of progress toward myopia than AL alone. In this study, AL/CRC changes were analyzed after posterior scleral reinforcement(PSR) for pathologic myopia.
Methods :
This study enrolled 32 pathologic myopic eyes with AL≥25mm (26patients) treated with PSR (PSR group) from January 2014 to December 2016 in Shenzhen Eye Hospital. At the same time 35 pathologic myopic eyes with posterior staphyloma (23 patients) untreated (control group), which were age, gender, AL, refractive error and best corrected visual acuity (BCVA) matched with the status of the PSR group before surgery, were recruited. In PSR group, a buckle of bovine pericardium with a width of 6 to 10 mm was placed onto the sclera surface of the macula in pathological myopic eyes following the Thompson technique.Pathologic myopia with maculopathy, other ocular disease, and history of ocular surgery or ocular injury was excluded from this study. Axial length, refractive error, best corrected visual acuity, corneal radius of curvature and AL/CRC were evaluated during the one-year follow-up.
Results :
There were no statistical differences in each parameter between the two groups at baseline. Significant differences were found between the two groups in both axial elongation and best corrected visual acuity improvement.The mean value of axial elongation in the PSR group was 0.13±0.17 mm versus 0.71±1.08mm in the control group. The significant difference between the two groups (P＜0.05) suggested that the PSR surgery limited the axial elongation effectively. Before surgery,Axial length/ horizontal corneal radius of curvature ratio ( AL/hCRC) was 3.49±0.08 and at the one-year follow-up it was 3.48±0.08(P<0.05). The average AL/hCRC significantly decreased, while there were no significant changes in the control group. AL/CR ratio increased slower in the PSR group(0.01±0.01) than the control one(0.03±0.00), although this was not a statistically significant difference.
Conclusions :
Our study indicated that bovine pericardium can be an alternative for sclera in PSR Surgery. The surgery performed with bovine pericardiumcan effectively delay the axial elongation in pathological myopia. AL/hCRC significantly decreased, which may indicate less myopic progression after surgery.
This is an abstract that was submitted for the 2018 ARVO Annual Meeting, held in Honolulu, Hawaii, April 29 - May 3, 2018.