July 2018
Volume 59, Issue 9
Open Access
ARVO Annual Meeting Abstract  |   July 2018
Ultra-wide Field Fluorescein Angiography Guided Targeted Retinal Photocoagulation in Diabetic Retinopathy
Author Affiliations & Notes
  • Pallavi Singh
    Ophthalmology, All India Institute of Medical Sciences, New Delhi, Delhi, India
  • Atul Kumar
    Ophthalmology, All India Institute of Medical Sciences, New Delhi, Delhi, India
  • Parijat Chandra
    Ophthalmology, All India Institute of Medical Sciences, New Delhi, Delhi, India
  • Vinod Kumar
    Ophthalmology, All India Institute of Medical Sciences, New Delhi, Delhi, India
  • Footnotes
    Commercial Relationships   Pallavi Singh, None; Atul Kumar, None; Parijat Chandra, None; Vinod Kumar, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1900. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      Pallavi Singh, Atul Kumar, Parijat Chandra, Vinod Kumar; Ultra-wide Field Fluorescein Angiography Guided Targeted Retinal Photocoagulation in Diabetic Retinopathy. Invest. Ophthalmol. Vis. Sci. 2018;59(9):1900.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Purpose : Diabetic retinopathy is a leading cause of avoidable blindness in the world. Conventional scatter laser in diabetic retinopathy is associated with adverse effects like worsening of macular edema, loss of contrast sensitivity and other visual functions. Lesser invasive laser techniques are needed to overcome the problems associated with conventional laser. We performed a prospective interventional study to assess the effects of ultra-wide field fluorescein angiography (UWFFA) guided targeted retinal photocoagulation (TRP) in diabetic retinopathy.

Methods : Thirty eyes with severe non proliferative diabetic retinopathy (NPDR) and proliferative diabetic retinopathy (PDR) without high risk characteristics (HRC) were subjected to TRP of only capillary non-perfusion (CNP) areas as seen on UWFFA. The patients were followed up for a minimum of six months. Visual acuity, contrast sensitivity, central macular thickness, visual fields`and disease regression were assessed at baseline, 6 weeks, 3 months and 6 months after laser photocoagulation.

Results : There was a significant change in visual acuity from baseline to 6 weeks, amounting to a 10-letter improvement. The contrast sensitivity also increased from 1.05 to 1.2 (p<0.01), and mean deviation on visual fields also showed improvement (p <0.01). These changes remained stable at 3 and 6 months. There was no statistically significant difference in the central macular thickness over the course of observation. Eight eyes required additional laser and two eyes required injection of anti-VEGF at 3 months. Disease regression was seen in 93.3% eyes at 6 months.

Conclusions : UWFFA guided TRP is an effective treatment modality in eyes with severe NPDR and PDR without HRC. It results in disease regression in a good percentage of cases without any detrimental effects of laser induced worsening of macular edema and function.

This is an abstract that was submitted for the 2018 ARVO Annual Meeting, held in Honolulu, Hawaii, April 29 - May 3, 2018.

 

Ultra widefield guided targeted retinal photocoagulation in a treatment naive eye with PDR without HRC. A) Pre-laser FA showing multiple microaneurysms, mid-peripheral areas of neovascularization with leaks and peripheral capillary non-perfusion areas B) Post-laser FA at 3 months showing PASCAL laser of CNP areas with a single persistent neovascular leak requiring additional laser.

Ultra widefield guided targeted retinal photocoagulation in a treatment naive eye with PDR without HRC. A) Pre-laser FA showing multiple microaneurysms, mid-peripheral areas of neovascularization with leaks and peripheral capillary non-perfusion areas B) Post-laser FA at 3 months showing PASCAL laser of CNP areas with a single persistent neovascular leak requiring additional laser.

×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×