July 2018
Volume 59, Issue 9
Open Access
ARVO Annual Meeting Abstract  |   July 2018
CATARACT GRADING: ASSESSMENT OF A NEW OBJECTIVE AND AUTOMATIZED LENS DENSITY QUANTIFICATION METHOD USING OCT TECHNOLOGY INTEGRATED INTO THE IOLMASTER 700 AND COMPARISION WITH EXISTING METHODS
Author Affiliations & Notes
  • Christophe Panthier
    Dr Gatinel, Fondation Rothschild, Paris, France
  • Alice Wazieres
    Dr Gatinel, Fondation Rothschild, Paris, France
  • HELENE ROUGER
    Dr Gatinel, Fondation Rothschild, Paris, France
  • Alain SAAD
    Dr Gatinel, Fondation Rothschild, Paris, France
    American university, Beyrouth, Lebanon
  • Damien Gatinel
    Dr Gatinel, Fondation Rothschild, Paris, France
  • Footnotes
    Commercial Relationships   Christophe Panthier, None; Alice Wazieres, None; HELENE ROUGER, None; Alain SAAD, None; Damien Gatinel, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science July 2018, Vol.59, 2232. doi:
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      Christophe Panthier, Alice Wazieres, HELENE ROUGER, Alain SAAD, Damien Gatinel; CATARACT GRADING: ASSESSMENT OF A NEW OBJECTIVE AND AUTOMATIZED LENS DENSITY QUANTIFICATION METHOD USING OCT TECHNOLOGY INTEGRATED INTO THE IOLMASTER 700 AND COMPARISION WITH EXISTING METHODS. Invest. Ophthalmol. Vis. Sci. 2018;59(9):2232.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To assess a new objective automatized cataract grading method based on lens densitometry on Swept-Source Optical Coherence Tomography (SS-OCT) scans provided by the IOLMaster 700

Methods : SETTINGS: Single centre study at the Rothschild Foundation, Paris, France.
DESIGN: Prospective cross-sectional study
METHODS: All patients consulting for cataract evaluation who provided their consent to participate in the study were included. History of eye surgery, cornea or retina disorders, and ocular dryness were exclusion criteria. The average lens densitometry (ALD) was automatically measured on SS-OCT scans provided by the IOLMaster 700 using Matlab® algorithm. The ocular scatter index (OSI) measured with a double-pass aberrometer (OQAS®), the “Pentacam Nucleus Staging” (PNS) score and mean PNS were also measured and compared to the ALD.

Results : Two hundred fifty nine eyes ( 154 with cataract and 85 controls) were included. The average lens densitometry measurements were repeatable (P = .99, analysis of variance). The repeatability limit was 2.50 pixel unit. The average lens density correlated with the OSI (r2 = 0.52, P < .01), nuclear staging score (r2 = 0.40, P < .01) and mean nuclear staging (r2 = 0.67, P < .01). The area under the curve (ROC analysis) was 0.967 for ALD (0.962 and 0.917 for OQAS and PNS respectively). An average lens density greater than 74 pixel units was the cutoff threshold for cataract with 96% of sensitivity and 91% of specificity.

Conclusions : The average lens density measured by SS-OCT is a repeatable and reliable objective cataract grading method. It correlates with OSI measurement. In case of average lens density greater than 74 pixel units, cataract surgery may be discussed if patient has visual impairment.

This is an abstract that was submitted for the 2018 ARVO Annual Meeting, held in Honolulu, Hawaii, April 29 - May 3, 2018.

 

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