July 2018
Volume 59, Issue 9
Open Access
ARVO Annual Meeting Abstract  |   July 2018
New Corneal Endothelial Severity Scoring System for Fuchs`s Endothelial Dystrophy: Horizontal cornea x Vertical cornea
Author Affiliations & Notes
  • Sabrina Marques Chammas
    ISCMSP, SÃO PAULO, Brazil
  • Richard Y Hida
    ISCMSP, SÃO PAULO, Brazil
  • Ricardo Holzchuh
    ISCMSP, SÃO PAULO, Brazil
  • F�bio Ursulino Reis Carvalho
    ISCMSP, SÃO PAULO, Brazil
  • ivan Corso Teixeira
    ISCMSP, SÃO PAULO, Brazil
  • Fernando Cesar Abib
    Federal University of Parana, Parana, Brazil
    ISCMSP, SÃO PAULO, Brazil
Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1362. doi:
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      Sabrina Marques Chammas, Richard Y Hida, Ricardo Holzchuh, F�bio Ursulino Reis Carvalho, ivan Corso Teixeira, Fernando Cesar Abib; New Corneal Endothelial Severity Scoring System for Fuchs`s Endothelial Dystrophy: Horizontal cornea x Vertical cornea. Invest. Ophthalmol. Vis. Sci. 2018;59(9):1362.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To provide a severity scoring system for Fuchs’ endothelial dystrophy (FED) based on corneal specular microscope (CSMe) image patterns. As secondary purpose, horizontal cornea scoring was compared with vertical scoring to confirm previous studies that shows that exposed areas of the cornea can show worse endothelial patterns.

Methods : A cross-sectional study involving 98 eyes of 49 patients with the clinical diagnosis of Fuchs’ endothelial dystrophy (FED) was performed at the Clinica de Olhos Dr. Fernando Abib (Curitiba, Brazil) and at Santa Casa de Misericordia de Sao Paulo (Sao Paulo, Brazil). Contact Corneal Specular Microscope (CSMe) (BioOptics, USA) was used to score the severity of FED based on CSMe endothelial profile (Figure 1). The following areas of the cornea were analyzed and scored by two different and independent examiners: Central (C), Superior (S), Superior Mid-Periphery (SMP), Inferior (I), Nasal (N), and Temporal (T). Results were expressed in average and standard deviation. Horizontal cornea scoring (C+N+T) was then compared with vertical cornea scoring (C+S+SMP+I) using Student’s t test with level of significance of 0.05

Results : Horizontal cornea (3.00 ± 2.38) showed statistical difference scoring when compared to vertical cornea scoring (2.48 ± 2.34) (p=0.0014)

Conclusions : Severity scoring system for FED was appropriate to classify the different areas of the cornea. Horizontal areas of the cornea seems to have a worse endothelial profile that the vertical areas

This is an abstract that was submitted for the 2018 ARVO Annual Meeting, held in Honolulu, Hawaii, April 29 - May 3, 2018.

 

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