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Richard Helms, Faruk Orge; Visualization of Structural Changes After Transscleral Cyclophotocoagulation Using 3D Reconstruction of UBM Images. Invest. Ophthalmol. Vis. Sci. 2018;59(9):1701.
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© ARVO (1962-2015); The Authors (2016-present)
To visualize structural changes in the ciliary body after transscleral cyclophotocoagulation (TSCPC) using three-dimensional reconstruction of two-dimensional images from ultrasonic biomicroscopy (UBM)
An enucleated human eye was imaged in 2D using a 50 MHz linear UBM probe attached to a servo-controlled translation stage. Roughly 1000 2D images were collected which include the entire ciliary body. Image acquisition time is approximately two minutes. The 2D images were registered, filtered, and assembled into a 3D model using various software platforms and relevant structures, such as the ciliary processes, were evaluated for changes.
The reconstructed 3D model is dimensionally accurate and provides a fully manipulable model of the iris and ciliary body. After TSCPC, changes in the ciliary processes were evident including overall shape and size.
With the addition of appropriate hardware and software, 2D UBM images can be reconstructed to provide a dimensionally-accurate 3D model of the anterior eye. This model allows clinicians to visualize changes in the ciliary processes seen after TSCPC which can aid in targeting the location and intensity of treatment and in evaluating the effectiveness of the treatment.
This is an abstract that was submitted for the 2018 ARVO Annual Meeting, held in Honolulu, Hawaii, April 29 - May 3, 2018.
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