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Eun Jung Lee, Jong Chul Han, Changwon Kee; Determinant factors of optic disc shape in myopic congenital glaucoma. Invest. Ophthalmol. Vis. Sci. 2018;59(9):2027.
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© ARVO (1962-2015); The Authors (2016-present)
To evaluate the components on determining the round and tilted shape of the optic disc in myopic congenital glaucoma.
Medical records of myopic congenital glaucoma patients who received surgery were reviewed. Data included age of onset, age at first surgery, intraocular pressure (IOP), corneal diameter, refractive error, and axial length. Patients were divided into tilted and round disc group according to the tilt ratio of optic disc. Clinical parameters were compared between the two groups using generalized estimation equation.
Twenty-eight tilted discs and 22 round discs were enrolled. First surgeries were performed earlier in tilted disc group at 2.0 ± 1.8 months, compared to 14.7 ± 9.5 months in round disc group (p=0.007). Tilted disc group showed earlier age of onset than that of round disc group (p<0.001). Degree of myopia by refraction and axial length were greater in tilted disc group (p=0.005 and 0.011).
In myopic congenital glaucoma patients, earlier onset and earlier normalization of IOP by surgery were associated with longer axial length and tilted optic disc, and later onset and later normalization of IOP were associated with round optic disc. Therefore, IOP elevation in more immature eyes would have altered sclera property and predisposed them to be more susceptible to eyeball elongation. Additionally, later onset and prolonged IOP elevation might have provoked sclera canal expansion in a round pattern and thereby induce round optic disc.
This is an abstract that was submitted for the 2018 ARVO Annual Meeting, held in Honolulu, Hawaii, April 29 - May 3, 2018.
The distribution age at first surgery and axial length in myopic congenital glaucoma patients.
The distribution age at first surgery and refractive error in myopic congenital glaucoma patients.
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