July 2018
Volume 59, Issue 9
Open Access
ARVO Annual Meeting Abstract  |   July 2018
Pentagram Suturing Anterior Chamber Plasty and Descemet’s Stripping Automated Endothelial Keratoplasty (DSAEK) for Bullous Keratopathy with Extensive Anterior Synechia of Iris
Author Affiliations & Notes
  • Xiang Fan
    Department of Ophthalmology, Peking University Third Hospital, Beijing, China
    Beijing Key Laboratory of Restoration of Damaged Ocular Nerve, Beijing, China
  • Yansheng Hao
    HNA Doctor Group, Beijing, China
    Beijing Key Laboratory of Restoration of Damaged Ocular Nerve, Beijing, China
  • Jing Hong
    Department of Ophthalmology, Peking University Third Hospital, Beijing, China
    Beijing Key Laboratory of Restoration of Damaged Ocular Nerve, Beijing, China
  • Wei Wang
    Department of Ophthalmology, Peking University Third Hospital, Beijing, China
    Beijing Key Laboratory of Restoration of Damaged Ocular Nerve, Beijing, China
  • Footnotes
    Commercial Relationships   Xiang Fan, None; Yansheng Hao, None; Jing Hong, None; Wei Wang, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science July 2018, Vol.59, 1304. doi:
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      Xiang Fan, Yansheng Hao, Jing Hong, Wei Wang; Pentagram Suturing Anterior Chamber Plasty and Descemet’s Stripping Automated Endothelial Keratoplasty (DSAEK) for Bullous Keratopathy with Extensive Anterior Synechia of Iris. Invest. Ophthalmol. Vis. Sci. 2018;59(9):1304.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To observe the effect of pentagram suturing anterior chamber plasty (PSACP) before DSAEK that help cure the bullous keratopathy with extensive anterior synechia of iris.

Methods : Two cases of bullous keratopathy patients with extensive anterior synechia of iris formed from intraocular pressure (IOP) well-controlled malignant glaucoma that post anterior vitrectomy were analyzed. Patient "A" received anterior chamber plasty with synechia separation and penetrating keratoplasty (PKP). Patient "B" received PSACP which had put pentagram sutures as a barrier in front of the anterior surface of the iris to prevent the iris from peripheral anterior synechia (PAS) to extensive anterior synechia, then the DSAEK would be performed. The prognosis of patient "A" and patient "B" were compared by the time (1 day, 1 week, 4 weeks, 12 weeks, 24 weeks) till the 360° PAS appeared on the anterior segment optical coherence tomography (ASOCT).

Results : On 12 weeks post-surgery, patient "A" showed 360°PAS with elevated IOP while patient "B" showed normal IOP and no PAS, even no edema in the cornea and endothelial graft. Moreover, patient "B" showed normal IOP and no PAS, no edema in the cornea and endothelial graft on 24 weeks post-surgery.

Conclusions : Pentagram suturing anterior chamber plasty might provide adequate space basis for DSAEK to help cure the bullous keratopathy with vanished anterior chamber.

This is an abstract that was submitted for the 2018 ARVO Annual Meeting, held in Honolulu, Hawaii, April 29 - May 3, 2018.

 

 

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