Abstract
Purpose :
To investigate the retinal vascular changes quantitatively, analyzing the early and further effects on the retinal circulation with 6-month follow-up after strabismus surgery.
Methods :
Consecutive patients who underwent strabismus surgery were enrolled prospectively. Color fundus photographs were evaluated preoperatively and on day 1, day 7 and 6-month postoperatively, to analyze the retinal arteries and average retinal arteriolar or venular width, which was calculated as the central retinal arteriolar equivalent(CRAE) or central retinal venular equivalent(CRVE). Arteriovenous ratio (AVR) was calculated as CRAE divided by CRVE.
Results :
One hundred and fifty-four eyes of 104 consecutive patients were included, with the mean age of 12.69±8.91 years (range: 3-51years). Compared with preoperative value (121.55±24.67), the mean CRAE on postoperative day 1 (131.18±28.29) was significantly increased (P=0.003), but went back to baseline level on postoperative day 7 (118.89±30.35，P=0.15), and 6-month(123.22±15.32, P=0.60). As for the mean CRVE, there were no significant difference between those four time points (preoperative value 172.43±33.25vspostoperative day 1 175.57±36.98vsday 7 174.03±40.18vs 6-month 174.86±20.46, P=1.00. The AVR on post-operative day 1 was significantly larger than preoperative value (0.75±0.09 vs. 0.70±0.07, P<0.001), but turned back to baseline level on day 7 (0.69±0.09, P=0.08) and 6-month (0.71±0.07, P=0.07). Of those 154 eyes, 84 eyes (54.55%) underwent surgery on single rectus muscle were further sub-grouped. For those 23 eyes underwent medial rectus recession, the same trend above of CRAE and AVR in different time points was found. However, the other 61 eyes underwent lateral rectus recession didn’t show any significant difference between four different time points.
Conclusions :
Strabismus surgery on horizontal rectus muscles may increase retinal blood flow during the early postoperative period, but would return to normal later. Those hemodynamic changes didn’t affect the structure and function of retina.
This abstract was presented at the 2019 ARVO Annual Meeting, held in Vancouver, Canada, April 28 - May 2, 2019.