July 2019
Volume 60, Issue 9
Open Access
ARVO Annual Meeting Abstract  |   July 2019
Incidence and Associated Risk Factors of Suspected Glaucoma and Glaucoma after Congenital Cataract Surgery: A Longitudinal Follow-up Study in China
Author Affiliations & Notes
  • Jinghui Wang
    Cataract, Zhongshan Ophthalmic Center, Guangzhou, Guangdong, China
  • Weirong Chen
    Cataract, Zhongshan Ophthalmic Center, Guangzhou, Guangdong, China
  • Yizhi Liu
    Cataract, Zhongshan Ophthalmic Center, Guangzhou, Guangdong, China
  • Haotian Lin
    Cataract, Zhongshan Ophthalmic Center, Guangzhou, Guangdong, China
  • Footnotes
    Commercial Relationships   Jinghui Wang, None; Weirong Chen, None; Yizhi Liu, None; Haotian Lin, None
  • Footnotes
    Support  the Science and Technology Planning Projects of Guangdong Province(2017B030314025)
Investigative Ophthalmology & Visual Science July 2019, Vol.60, 507. doi:
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      Jinghui Wang, Weirong Chen, Yizhi Liu, Haotian Lin; Incidence and Associated Risk Factors of Suspected Glaucoma and Glaucoma after Congenital Cataract Surgery: A Longitudinal Follow-up Study in China. Invest. Ophthalmol. Vis. Sci. 2019;60(9):507.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To investigate the incidence and associated risk factors of suspected glaucoma and glaucoma in congenital cataract patients after cataract surgery

Methods : A total of 746 eyes of 421 patients were diagnosed with congenital cataract at Zhongshan Ophthalmic Center from 2012 to 2017. Patients who underwent cataract surgery were included in this study and were classified into 3 groups according to postoperative intraocular pressure (IOP): a normal IOP group, a suspected glaucoma group and a glaucoma group. Multivariable cox regression analysis was performed to estimate the incidence and associated risks of postoperative suspected glaucoma and glaucoma.

Results : The risk of developing suspected glaucoma or glaucoma among the study eyes was 29.20% (123/421 eyes), and that of developing glaucoma among the suspected glaucoma eyes 11.38% (14/123 eyes). The incidence of glaucoma after pediatric cataract surgery was 3.32% (14/421 eyes). Our study revealed surgical procedure (surgery with primary IOL implantation vs that without IOL implantation, HR, 0.207; 95% CI, 0.096-0.449; P<0.0001; surgery with primary IOL implantation vs that with secondary IOL implantation, HR, 0.347; 95% CI, 0.169-0.711; P=0.0040) and anterior chamber depth (HR, 0.732; 95% CI, 0.587-0.911; P=0.0050) as important predictors of suspected glaucoma and glaucoma. Sex (P=0.163), cataract laterality (P=0.105) and age at surgery (P=0.424) were not significantly associated with suspected glaucoma or glaucoma in the Cox model.

Conclusions : Suspected glaucoma and glaucoma after pediatric cataract surgery should not be ignored in daily clinical practice. Pediatric cataract patients are at high risk of suspected glaucoma or glaucoma and require lifelong surveillance and real-time intervention.

This abstract was presented at the 2019 ARVO Annual Meeting, held in Vancouver, Canada, April 28 - May 2, 2019.

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