July 2019
Volume 60, Issue 9
Open Access
ARVO Annual Meeting Abstract  |   July 2019
Prediction for Effectiveness of Unilateral Selective Laser Trabeculoplasty for the Untreated Fellow Eye of Primary Open-angle Glaucoma Patients
Author Affiliations & Notes
  • Xiang Fan
    Peking University Eye Center, Peking University Third Hospital, Beijing, China
  • Lingling Wu
    Peking University Eye Center, Peking University Third Hospital, Beijing, China
  • Footnotes
    Commercial Relationships   Xiang Fan, None; Lingling Wu, None
  • Footnotes
    Support  None.
Investigative Ophthalmology & Visual Science July 2019, Vol.60, 684. doi:
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      Xiang Fan, Lingling Wu; Prediction for Effectiveness of Unilateral Selective Laser Trabeculoplasty for the Untreated Fellow Eye of Primary Open-angle Glaucoma Patients. Invest. Ophthalmol. Vis. Sci. 2019;60(9):684.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To explore correlative factors for predicting effectiveness of unilateral selective laser trabeculoplasty (SLT) for untreated eyes of open-angle glaucoma (OAG) patients.

Methods : This was a self-controlled prospective study. 30 OAG patients under same anti-glaucoma medications for both eyes were included. SLT was performed for the poorly controlled eye for each patient. Intraocular pressure (IOP) was followed-up for 6 months with all medications remained unchanged. Success rates were calculated with the criteria of IOP reduction≥20%. Correlative factors were analyzed between successful and unsuccessful untreated eyes at the end of follow-up.

Results : For untreated eyes, preoperative mean IOP was 17.4±2.4mmHg and 33.3% of these eyes had an elevated IOP at 1 hour post SLT; mean percentage of IOP reductions for 1 week, 1month, 3 months, and 6 months after SLT was 6±12%, 5±17%, 14±13%, 14±12%; success rates were 10.0%, 16.7%, 33.3% and 30.0% respectively. Treated eyes were similar with untreated eyes in preoperative mean IOP and IOP reductions(p>0.05), whereas with higher rate of elevated IOP at 1 hour post SLT (56.7%, p<0.05). Untreated eyes whose IOP reduction≥20% at 6 months after SLT had higher preoperative IOP, energy of SLT, rate of elevated IOP at 1 hour post SLT and success rate in treated eyes (p<0.05).

Conclusions : In poorly controlled OAG eyes under anti-glaucoma medications, unilateral SLT created continuous IOP reduction effects for such untreated eyes. Preoperative IOP, energy of SLT, rate of elevated IOP at 1 hour post SLT and success rate in treated eyes were correlative factors for predicting success rate of untreated eyes at 6 months after SLT.

This abstract was presented at the 2019 ARVO Annual Meeting, held in Vancouver, Canada, April 28 - May 2, 2019.

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