Abstract
Purpose :
The aim of this study was to compare the efficacy and safety of transscleral micropulse cyclophotocoagulation (MPC) applied at the level of the pars plicata (PLI-MPC) versus at the pars plana (PLA-MPC).
Methods :
In this prospective interventional case series, 45 eyes of 29 medically treated open-angle gaucoma patients scheduled for MPC (IRIDEX IQ810 Laser Systems, CA) for further IOP reduction were included. Twenty-seven eyes underwent PLI-MPC and 18 eyes PLA-MPC. Twenty-four hour mean intraocular pressure (IOP) reduction 3 months after the procedure, and complications were compared between both groups. Statistical analyses were performed with SPSS. Pre- and postoperative IOP differences between the two treatment groups were carried out using a linear mixed model.
Results :
In the PLI-MPC group (mean age: 75.41 ± 5.92 years), 24 hour mean IOP was reduced from 15.8 ± 2.9 mmHg to 13.9 ± 2.9 mmHg at 3 months (P=0.005). In the PLA-MPC group (mean age: 75.17 ± 8.67 years), mean IOP decreased from 16.5 ± 3.3 mmHg to 14.0 ± 2.8 mmHg (P=0.003). No complications were reported in either group. There were no correlations between IOP reduction and age, gender, high or normal pressure glaucoma or the severity of the visual field.
Conclusions :
PLI-MPC and PLA-MPC seem to be safe and effective in lowering the IOP of patients with treated open-angle glaucoma. Both modes of application showed a statistically significant IOP lowering.
This abstract was presented at the 2019 ARVO Annual Meeting, held in Vancouver, Canada, April 28 - May 2, 2019.