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Vidal Soberón, Yuoming Yang, James Lamb, Philip E Chow, Tara A McCannel; "Doughnut" shaped braquitherapy plaque for the treatment of Iris melanoma. Invest. Ophthalmol. Vis. Sci. 2019;60(9):717.
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© ARVO (1962-2015); The Authors (2016-present)
To present a custom made brachytherapy plaque for the treatment of iris melanoma
A retrospective review of iris melanoma cases treated at Jules Stein Eye Institute with a custom doughnut shaped plaque was performed
Six patients received treatment with the custom brachytherapy plaque for Iris Melanoma between 9/2015 and 7/2018. In all cases a control of the primary tumor was achieved. Three patients maintained excellent visual acuity after the procedure. Two patients had to undergo filtrating surgery for glaucoma. No cases developed corneal decompensation. One patient later developed madarosis.
This custom designed plaque is adequate for treating iris melanoma. A doughnut shape plaque design may be able to spare the cornea form receiving full radiation dose by shifting the radioactive material to the iris plane instead of over the cornea. Modifying plaque design can also have unexpected effects such as increasing the radiation dose the eyelids get with brachytherapy.
This abstract was presented at the 2019 ARVO Annual Meeting, held in Vancouver, Canada, April 28 - May 2, 2019.
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