July 2019
Volume 60, Issue 9
Open Access
ARVO Annual Meeting Abstract  |   July 2019
"Doughnut" shaped braquitherapy plaque for the treatment of Iris melanoma
Author Affiliations & Notes
  • Vidal Soberón
    Retina, Asociacion para evitar la ceguera en mexico, Mexico city, DF, Mexico
    Retina/Oncology, Jules Stein Eye Institute, Los Angeles, California, United States
  • Yuoming Yang
    Radiation Oncology, UCLA, Los Angeles, California, United States
  • James Lamb
    Radiation Oncology, UCLA, Los Angeles, California, United States
  • Philip E Chow
    Radiation Oncology, UCLA, Los Angeles, California, United States
  • Tara A McCannel
    Retina/Oncology, Jules Stein Eye Institute, Los Angeles, California, United States
  • Footnotes
    Commercial Relationships   Vidal Soberón, None; Yuoming Yang, None; James Lamb, None; Philip Chow, None; Tara McCannel, None
  • Footnotes
    Support  none
Investigative Ophthalmology & Visual Science July 2019, Vol.60, 717. doi:
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    • Get Citation

      Vidal Soberón, Yuoming Yang, James Lamb, Philip E Chow, Tara A McCannel; "Doughnut" shaped braquitherapy plaque for the treatment of Iris melanoma. Invest. Ophthalmol. Vis. Sci. 2019;60(9):717.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To present a custom made brachytherapy plaque for the treatment of iris melanoma

Methods :
A retrospective review of iris melanoma cases treated at Jules Stein Eye Institute with a custom doughnut shaped plaque was performed

Results : Six patients received treatment with the custom brachytherapy plaque for Iris Melanoma between 9/2015 and 7/2018. In all cases a control of the primary tumor was achieved. Three patients maintained excellent visual acuity after the procedure. Two patients had to undergo filtrating surgery for glaucoma. No cases developed corneal decompensation. One patient later developed madarosis.

Conclusions : This custom designed plaque is adequate for treating iris melanoma. A doughnut shape plaque design may be able to spare the cornea form receiving full radiation dose by shifting the radioactive material to the iris plane instead of over the cornea. Modifying plaque design can also have unexpected effects such as increasing the radiation dose the eyelids get with brachytherapy.

This abstract was presented at the 2019 ARVO Annual Meeting, held in Vancouver, Canada, April 28 - May 2, 2019.

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